X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) Antikörper

Antigen: X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3)

Klonalität: Polyklonal

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN137699

Produktbeschreibung

Weitere Bezeichnung: XRCC3

Immunogen: Human XRCC3, over-expressed in E. coli

Isotyp: IgG1  (Passende Sekundärantikörper)

Beschreibung: Five human RAD51 homologs have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologs interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes.XRCC3 (x-ray cross complementing) was first identified as a human gene complementing the DNA damage sensitivity, chromosonal instability and impaired growth of the mutant hamster cell line irs1SF. This fact coupled with XRCC3 being a member of the RAD51 gene family have implied a role in the repair of DNA damage by homologous recombination.

Spezifität: This antibody is specific for XRCC3

Anwendungen

Applikationshinweise: WB: Use at a dilution of 1/1000. A band of ~40kDa should be detected. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Konzentration: 6.2 mg/ml

Reinheit: Ascitic fluid

Buffer: n/a

Lagerung: Store at -20 C. Avoid repeated freeze-thaw cycles.

Forschungsgebiet: Chromatin und nukleäre Signaltransduktion, Chromatin-Bindungsproteine, DNS/RNS

Beschränkungen: Nur für Forschungszwecke einsetzbar