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CD72.1 Antikörper (FITC)

Reaktivität: Maus FACS Wirt: Maus Monoclonal 10-1-D2 FITC
Produktnummer ABIN135265
  • Target Alle CD72.1 Produkte
    CD72.1
    Reaktivität
    Maus
    Wirt
    • 7
    Maus
    Klonalität
    • 7
    Monoklonal
    Konjugat
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser CD72.1 Antikörper ist konjugiert mit FITC
    Applikation
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD72.1, Mr 45 kDa
    Produktmerkmale
    Mouse Anti-Mouse CD72.1-FITC
    Aufreinigung
    Ion exchange
    Immunogen
    DBA/2 mouse spleen cells
    Klon
    10-1-D2
    Isotyp
    IgG2b
  • Applikationshinweise
    • Applications: FC - Quality tested , IP - Reported in literature , Activ - Reported in literature , Block - Reported in literature , Costim - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells APC and AF647 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Kommentare

    In vitro blocking and proliferation assays

    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg in 1.0 mL of PBS/Sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C
  • Target
    CD72.1
    Abstract
    CD72.1 Produkte
    Hintergrund
    CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing.
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