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L-Selectin Antikörper (FITC)

SELL Reaktivität: Maus FACS Wirt: Ratte Monoclonal MEL-14 FITC
Produktnummer ABIN135250
  • Target Alle L-Selectin (SELL) Antikörper anzeigen
    L-Selectin (SELL) (Selectin L (SELL))
    Reaktivität
    • 99
    • 76
    • 41
    • 29
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 96
    • 67
    • 49
    Ratte
    Klonalität
    • 159
    • 48
    • 3
    Monoklonal
    Konjugat
    • 73
    • 28
    • 23
    • 16
    • 13
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser L-Selectin Antikörper ist konjugiert mit FITC
    Applikation
    • 157
    • 56
    • 56
    • 53
    • 35
    • 31
    • 17
    • 13
    • 12
    • 10
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD62L, Mr 74 kDa on lymphocytes and Mr 95 kDa on neutrophils
    Produktmerkmale
    Rat Anti-Mouse CD62L-FITC
    Aufreinigung
    Ion exchange column
    Immunogen
    C3H/eb cloned mouse B cell lymphoma 38C-13
    Klon
    MEL-14
    Isotyp
    IgG2a
    Top Product
    Discover our top product SELL Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , Cyto - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PACBLU conjugate 0.3 g/106 cells PE, APC, SPRD, PE/CY7, APC/CY7, AF488, AF647, and AF700 0.1 g/106 cells conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Kommentare

    In vivo and in vitro blocking of adhesion, Cytotoxicity studies

    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg in 1.0 mL of PBS/Sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C
  • Target
    L-Selectin (SELL) (Selectin L (SELL))
    Andere Bezeichnung
    CD62L (SELL Produkte)
    Synonyme
    CD62L antikoerper, LAM1 antikoerper, LECAM1 antikoerper, LEU8 antikoerper, LNHR antikoerper, LSEL antikoerper, LYAM1 antikoerper, PLNHR antikoerper, TQ1 antikoerper, A.11 antikoerper, L-selectin antikoerper, LECAM-1 antikoerper, SELE antikoerper, AI528707 antikoerper, Lnhr antikoerper, Ly-22 antikoerper, Ly-m22 antikoerper, Lyam-1 antikoerper, Lyam1 antikoerper, selectin L antikoerper, selectin, lymphocyte antikoerper, SELL antikoerper, Sell antikoerper
    Substanzklasse
    Chemical
    Hintergrund
    CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and Epidermal Growth Factor-like domains. It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes and eosinophils. This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells.
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