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BAX Antikörper (AA 3-16)

BAX Reaktivität: Maus WB, ELISA, IP Wirt: Maus Monoclonal 5B7 unconjugated
Produktnummer ABIN135026
  • Target Alle BAX Antikörper anzeigen
    BAX (BCL2-Associated X Protein (BAX))
    Bindungsspezifität
    • 41
    • 32
    • 19
    • 18
    • 15
    • 11
    • 10
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-16
    Reaktivität
    • 262
    • 157
    • 145
    • 46
    • 31
    • 28
    • 25
    • 18
    • 17
    • 11
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 168
    • 101
    • 4
    • 2
    Maus
    Klonalität
    • 181
    • 94
    Monoklonal
    Konjugat
    • 145
    • 16
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BAX Antikörper ist unkonjugiert
    Applikation
    • 243
    • 113
    • 74
    • 64
    • 53
    • 52
    • 52
    • 45
    • 42
    • 14
    • 12
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Spezifität
    Mouse Bax
    Produktmerkmale
    Mouse Anti-Mouse Bax-UNLB
    Aufreinigung
    Purified
    Immunogen
    Murine Bax peptide (a.a. 3-16)
    Klon
    5B7
    Isotyp
    IgG1
    Top Product
    Discover our top product BAX Primärantikörper
  • Applikationshinweise
    Working Dilution:
    Western Blotting: 1 µg/mL
    Representative data are included in this product insert.

    Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Product is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    4 °C
  • Target
    BAX (BCL2-Associated X Protein (BAX))
    Andere Bezeichnung
    Bax (BAX Produkte)
    Synonyme
    BAX-ALPHA antikoerper, bax-A antikoerper, xBax antikoerper, xlbax antikoerper, BAX antikoerper, bax antikoerper, fj16e01 antikoerper, wu:fc50b10 antikoerper, wu:fj16e01 antikoerper, BCL2L4 antikoerper, zgc:112983 antikoerper, BCL2 associated X, apoptosis regulator antikoerper, BCL2-associated X protein L homeolog antikoerper, BCL2-associated X protein antikoerper, bcl2-associated X protein, a antikoerper, bcl2-associated X protein, b antikoerper, BAX antikoerper, bax.L antikoerper, bax antikoerper, baxa antikoerper, Bax antikoerper, baxb antikoerper
    Hintergrund
    Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. Bax is a member of the Bcl-2 family of apoptosis-associated proteins and, although it is similar in structure to Bcl-2, Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells. Bax targets mitochondrial membranes, inducing mitochondrial damage and subsequent cell death in a caspase-independent manner, presumably via their ion channel-forming activity. These channels may then function to promote a mitochondrial permeability transition or to puncture the outer mitochondrial membrane. In addition to forming homodimer, Bax can heterodimerize with Bcl-2 and Bcl-XL proteins. This heterodimerization between pro- and anti-apoptotic family members may serve a titration function and act as a sensor for the programmed cell death program. Mab 5B7 is specific for mouse Bax.
    Pathways
    p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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