RT1-BB Antikörper (FITC)

Produktnummer ABIN133224

Produktdetails anti-RT1-BB Antikörper (FITC)

Target: RT1-BB (RT1 Class II, Locus Bb (RT1-BB))

Reaktivität: Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RT1-BB Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Spezifität: Rat RT1.Bu ( Rat Ia-polymorphic)

Aufreinigung: Purified from ascites via Protein G Chromatography

Immunogen: Rat thymocyte membrane glycoprotein . Fusion Partner: P3-NS1-1-Ag4 (NS1/1) . Donor: BALB/c spleen

Klon: OX-3

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.1 mg/ml

Buffer: FITC conjugated Ig buffered in PBS, 0.02% NaN and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu RT1-BB

Target: RT1-BB (RT1 Class II, Locus Bb (RT1-BB))

Andere Bezeichnung: RT1.B (RT1-BB Produkte)

Synonyme: RT1.B antikoerper, RT1 class II, locus Bb antikoerper, RT1-Bb antikoerper

Hintergrund: Anti-rat RT1.Bu monoclonal antibody recognizes a polymorphic determinant on rat Ia present on Lewis, Wistar, and AO rat strains (although it is apparently expressed in lower amounts in AO rats) but not BN, DA, or PVG/c strains (1,2). This antibody also cross-reacts with mouse strains (MHC haplotypes b and s ) and analysis of recombinant mouse strains shows that the determinant maps to the I-A region and correlates with mouse Ia specificity 9 (1). ABIN133224recognizes Ia antigens on approximately 18% of thymocytes but does not significantly label the majority of peripheral T lymphocytes (1,3,4). Thus, ABIN133224is particularly useful for distinguishing Ia positive cells from different rat strains and has been used in the recognition of cells of donor origin in bone marrow reconstituted radiation chimeras (3,4).

Pathways: Production of Molecular Mediator of Immune Response