HAT1 Antikörper

Antigen: HAT1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN131222

Produktbeschreibung

Weitere Bezeichnung: HAT-1

Immunogen: Synthetic peptide surrounding amino acid 445 of human HAT-1.

Beschreibung: Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation, DNA synthesis, and repair. Histone acetyltransferases and deacetylases are, respectively, the enzymes devoted to the addition and removal of acetyl groups from lysine residues on the histone N-terminal tails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders, including cancer.

Spezifität: The antibody recognizes 50 kDa HAT-1 from samples of human, mouse and rat origins. Reactivity to other species has not been determined.

Anwendungen

Applikationshinweise: The antibody can be used for Western blotting (1-2 µg/ml). However, the optimal concentrations should be determined individually.

Buffer: Supplied as 100 µg (0.2 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.

Beschränkungen: Nur für Forschungszwecke einsetzbar