In den Warenkorb
Bestellen Sie auch über:
 |
+49 (0)241 95 163 153 |
 |
+49 (0)241 95 163 155 |
Presenilin 1 (PSEN1) Antikörper
| Antigen | Presenilin 1 (PSEN1) |
| Synonyme | AD3, FAD, PS1, S182, Ad3h, PS-1, pre1, psen, zfPS1, zf-PS1, PSEN1, ad3, fad, ps1, s182, X-PS-beta, X-PS-alpha, DKFZp469K2026 |
| Klonalität | Polyklonal |
| Wirt |
 Alternativen Kaninchen |
| Reaktivität |
Alternativen Human, Maus, Ratte (Rattus) |
| Applikation |
Alternativen Western Blot (WB)
|
| Produktnummer | ABIN131054 |
| Menge | 100 µg |
| Preis | 280,00 € Zzgl. Versandkosten €20,00, €20,00 Trockeneispauschale sowie MWSt |
| Lieferung nach |
|
| Verfügbarkeit | Lieferung in 10 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | Presenilin 1 |
| Isotyp | IgG, Ig Fraction (Passende Sekundärantikörper) |
| Beschreibung | Presenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer’s disease, probably functioning through its associated .-secretase activity for amyloid-ß protein processing. Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed N-terminal (34 kDa) and C-terminal (~20 kDa) fragments. |
| Spezifität | The antibody recognizes Presenilin 1 of human, mouse, and rat origins. Reactivity to other species has not been tested. |
Anwendungen
| Applikationshinweise | The antibody can be used for Western blotting (2-4 µg/ml). However, the optimal concentrations should be determined individually. |
| Buffer | Supplied as 100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide. |
| Forschungsgebiet | Alzheimer-Krankheit (Morbus Alzheimer) |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "Presenilin 1 (PSEN1)", Typ "Antikörper" finden
| Wirte | Kaninchen (56), Ziege (9), Maus (6), Huhn (2) |
| Reaktivitäten | Human (66), Maus (26), Ratte (Rattus) (24), Affe (9), Hamster (3), Primate (1) |
| Applikationen | Western Blot (WB) (59), Immunhistochemie (Paraffinschnitte) (IHC (p)) (24), Enzyme Immunoassay (EIA) (21), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (15), ELISA (12), Immunhistochemie (IHC) (9), Immunpräzipitation (IP) (7), Immunfluoreszenz (IF) (6), Durchflusszytometrie (FACS) (4), Immunzytochemie (ICC) (1) |
| Epitope | N-Term (6), C-Term (5), Center (2), pSer357 (1) |
