WRNIP1 Antikörper (Internal Region, Isoform 1, Isoform 2)

Produktnummer ABIN129611

Produktdetails anti-WRNIP1 Antikörper

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Bindungsspezifität: Internal Region, Isoform 1, Isoform 2

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WRNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Maus, Ratte (Rattus), Affe

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of the WHIP1 protein. The immunogen sequence shows 100% homology to human WHIP1 and WHIP2 with predicted molecular weights of 72.2 kDa and 69.5 kDa, respectively. The immunogen sequence also shows 100% homology to WHIP1 from mouse, rat and monkey sequences. Reactivity with WHIP proteins from other sources is not known, but is likely due to reported homologies.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in western blotting against HEK293 whole cell lysates.  The antibody is also functional by ELISA.  Dilutions for western blotting represent a starting point dilution and further optimization may be required.  The antibody detects a band of approximately 96.0 kDa (predicted molecular weight: 72.2 kDa). Specific band detection by western blot is blocked by pre-incubating the antibody with the immunizing peptide prior to reaction with the membrane.  Reactivity in other immunoassays is unknown.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.10 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu WRNIP1

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Andere Bezeichnung: WHIP (WRNIP1 Produkte)

Synonyme: WRNIP1 antikoerper, wrnip1 antikoerper, RP11-420G6.2 antikoerper, WHIP antikoerper, bA420G6.2 antikoerper, zgc:85976 antikoerper, 4833444L21Rik antikoerper, Wrnip antikoerper, Whip antikoerper, Werner helicase interacting protein 1 antikoerper, Werner helicase interacting protein 1 L homeolog antikoerper, ATPase WRNIP1 antikoerper, WRNIP1 antikoerper, wrnip1.L antikoerper, wrnip1 antikoerper, EDI_075920 antikoerper, CpipJ_CPIJ017857 antikoerper, PITG_07216 antikoerper, VDBG_02914 antikoerper, Wrnip1 antikoerper, PGTG_08805 antikoerper

Hintergrund: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging.  Werner helicase interacting protein 1 (WHIP) interacts with the N-terminal portion of Werner protein, which contains an exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene product may influence the aging process.  A second isoform exists (WHIP2).
Synonyms: ATPase WRNIP 1 antibody, ATPase WRNIP1 antibody, bA420G6.2 antibody, FLJ22526 antibody, Putative helicase RUVBL antibody, RP11 420G6.2 antibody, Werner helicasae interacting protein 1 antibody

Gen-ID: 56897, 55661735

UniProt: Q96S55