FANCC Antikörper (AA 96-112)

Produktnummer ABIN129608

Produktdetails anti-FANCC Antikörper

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Bindungsspezifität: AA 96-112

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Schimpanse

Produktmerkmale: Concentration Definition: by UV absorbance at 280 nm

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 96-112 of Human FANCC.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 63 kDa in size corresponding to FANCC by western blotting in the appropriate human tissue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.45 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu FANCC

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Andere Bezeichnung: FANCC (FANCC Produkte)

Synonyme: zgc:154105 antikoerper, FANCC antikoerper, fa3 antikoerper, fac antikoerper, facc antikoerper, FA3 antikoerper, FAC antikoerper, FACC antikoerper, BB116513 antikoerper, Facc antikoerper, Fanconi anemia complementation group C antikoerper, Fanconi anemia, complementation group C antikoerper, Fanconi anemia complementation group C L homeolog antikoerper, FANCC antikoerper, fancc antikoerper, fancc.L antikoerper, Fancc antikoerper

Hintergrund: FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function.  FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM.  FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm.  This protein is ubiquitously expressed.  Defects in FANCC are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and
Synonyms: bA80I15.1 antibody, FA 3 antibody, FA3 antibody, FAC antibody, FACC antibody, Fanconi anemia complementation group C antibody

Gen-ID: 2176, 56118236

UniProt: Q00597

Pathways: DNA Reparatur