PRKG1 Antikörper (N-Term)

Produktnummer ABIN127130

Produktdetails anti-PRKG1 Antikörper

Target: PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody recognizes 75 kDa and 85 kDa PKG, corresponding to the Molecular Mass of twho PKG isoforms.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide near the N-terminus of Human PKG.

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 4-8 μg/mL. Immunohistochemistry: 4-8 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, 0.01 % Thimerosal, 30 % Glycerol, 0.5 % BSA

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu PRKG1

Target: PRKG1 (Protein Kinase, CGMP-Dependent, Type I (PRKG1))

Andere Bezeichnung: CGK1 (PRKG1 Produkte)

Synonyme: prkg1 antikoerper, zgc:63955 antikoerper, Pkgi antikoerper, cGk1 antikoerper, 1 antikoerper, PKG antikoerper, PRKG1B antikoerper, PRKGR1B antikoerper, cGK antikoerper, cGK 1 antikoerper, cGK1 antikoerper, cGKI antikoerper, cGKI-BETA antikoerper, cGKI-alpha antikoerper, CGKI antikoerper, cGKI-beta antikoerper, AW125416 antikoerper, Gm19690 antikoerper, Prkg1b antikoerper, Prkgr1b antikoerper, Prkg1beta antikoerper, protein kinase, cGMP-dependent, type Ia antikoerper, protein kinase, cGMP-dependent, type I antikoerper, protein kinase, cGMP-dependent, type 1 antikoerper, prkg1a antikoerper, PRKG1 antikoerper, prkg1 antikoerper, Prkg1 antikoerper

Hintergrund: PKGs are cyclic GMP-dependent protein kinases (also designed cGKs) that are classified into two types, PKGI and PKGII. Studies have shown that cGKs and cyclic AMP-dependent kinases (cAKs) are highly homologous protein kinase families with similar substrate specificities. Phosphorylation of cellular proteins by both families of kinases leads to alterations in calcium mobilization, protein phosphatase activity, ion channel function, gene transcription, smooth muscle contractility and platelet aggregation. However, recent studies using mice deficient in PKGs have shown that cGMP kinases regulate very specifically distinct pathways which are separate from those used by cyclic AMP kinases.Synonyms: CKG1A, CKG1B, PGK, PKG, PRKG1, PRKGR1A, PRKGR1B, cGKI-alpha, cGMP-dependent protein kinase 1

Gen-ID: 5592

NCBI Accession: NP_001091982

UniProt: Q13976