Calicin (CCIN) Antikörper

Antigen: Calicin (CCIN)

Synonyme: CCIN, MGC133688, Ccin, MGC94933, 4933417A14Rik

Klonalität: Polyklonal

Wirt: Meerschweinchen

Reaktivität: Rind (Kuh), Human

Applikation: Immunhistochemie (Gefrierschnitte) (IHC (fro)), Western Blot (WB)

Produktnummer: ABIN126100

Produktbeschreibung

Produktmerkmale: Synonyms: CCIN

Weitere Bezeichnung: Calicin

Swiss-Prot: Q28068

Immunogen: Synthetic N-terminal domain (aa 1-24) of bovine calicin, coupled to KLH.

Format: Serum

Beschreibung: Calicin is a basic protein of the sperm head cytoskeleton, necessary for normalmorphology during sperm differentiation. This protein contains kelch repeats and aBTB/POZ domain and is intronless.

Spezifität: Sperm head calyx protein calicin (mw 66,889, IEP 8. 1, 588 amino acids), testis specificcytoskeletal protein Homologue to kelch protein of the ring canal structure of Drosophilaovaries. Useful to study spermiogenetic differentiation. Calicin is absent from pathologicforms like roundheaded or other post-acrosomal sheath defect sperm malformations. Species: Human, Bovine, Rabbit, Rat, Mouse. Others not tested.

Anwendungen

Applikationshinweise: Immunohistochemistry on frozen: 1/100, 1h at RT. Western blot: 1/2000 (ECL). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Lagerung: Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.

Forschungsgebiet: Reproduktion, Zytoskelett, Mikrofilamente

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: von Buelow, Heid, Hess et al.: "Molecular nature of calicin, a major basic protein of the mammalian sperm head cytoskeleton." in: Experimental cell research, Vol. 219, Issue 2, pp. 407-13, 1995 (PubMed).