Insulin (INS) Antikörper

Antigen: Insulin (INS)

Synonyme: ILPR, IRDN, INS, MGC159719, ins1, xins, ins1-a, Insulin

Klonalität: Monoklonal (IN-05)

Wirt: Maus

Reaktivität: Human, Schwein, Rind (Kuh)

Applikation: Funktionale Studien (Func), Immunhistochemie (Paraffinschnitte) (IHC (p)), ELISA, Radioimmunoassay (RIA), Immunzytochemie (ICC)

Produktnummer: ABIN125702

Produktbeschreibung

Weitere Bezeichnung: Insulin

Immunogen: Porcine insulin.

Format: Azide Free

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: IN-05

Beschreibung: Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within thepancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulinresults in diabetes mellitus, one of the leading causes of morbidity and mortality in thegeneral population.

Spezifität: The antibody IN-05 reacts with insulin, one of the major regulatory endocrine hormones ofintermediate metabolism, normally secreted by the beta cells (a type of islet cells) of thepancreas, it is also present in tumors of B cell origin such as insulinoma.

Anwendungen

Applikationshinweise: Functional Application: The antibody IN-05 blocks binding of insulin to the receptor.

Konzentration: 1 mg/ml

Reinheit: > 95% (by SDS-PAGE)

Reinigung: Purified from ascites by protein-A affinity chromatography.

Buffer: Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 µ m filter sterilized.

Lagerung: Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.

Forschungsgebiet: Neurologie, Diabetes, Hormone

Beschränkungen: Nur für Forschungszwecke einsetzbar