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Cyclin D1 (CCND1) Antikörper

Antigen

Cyclin D1 (CCND1)

Synonyme
BCL1, PRAD1, U21B31, D11S287E, cD1, Cyl-1, bcl-1, AI327039, DIP1, GCIP, Maid, SECC-8, SSEC-8, AU022347, cb161, cycd1, fb52e01, fc83a12, id:ibd1198, wu:fb52e01, wu:fc83a12, MGC109078, ccnd1b, MGC52909, ... mehr anzeigen
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN125635
Menge 500µl  (100ug/ml approximately)  (Varianten)
Preis 263,46 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung

Weitere Bezeichnung Cyclin D1
Immunogen A synthetic peptide from c-terminus of human cyclin D1.
Format Ig-fraction, Purified
Spezifität This antibody reacts with a 36 kD protein. Cyclin D1 or PRAD-1 or bcl-1 is one of the key cell cycle regulators and functions in association with cdk4 and / or cdk6 by phosphorylating the Rb protein. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms including mantle cell lymphomas (MCL). This antibody reacts with mouse and rat.
Synonyme BCL1, PRAD1, U21B31, D11S287E, cD1, Cyl-1, bcl-1, AI327039, DIP1, GCIP, Maid, SECC-8, SSEC-8, AU022347, cb161, cycd1, fb52e01, fc83a12, id:ibd1198, wu:fb52e01, wu:fc83a12, MGC109078, ccnd1b, MGC52909, MGC132138, ccnd1, MGC53090, bcl1, prad1, u21b31, MGC69515, d11s287e, CCND1, ccndbp1, MGC137744, ZHM, CCNDBP1, MGC133757, DKFZp468E2216, DKFZp469C1216, DKFZp469H0317

Anwendungen

Applikationshinweise Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:200 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Breast carcinoma, mantle cell lymphoma. Cellular localization: Nuclear
Konzentration 100ug/ml approximately
Buffer Purified immunoglobulin fraction of rabbit antiserum against Cyclin D1 containing sodium azide as preservative.
Lagerung Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Forschungsgebiet Zellzyklus
Beschränkungen Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Alternativen

Alternativen zu Antigen "Cyclin D1 (CCND1)", Typ "Antikörper" finden
Wirte Kaninchen (75), Maus (43), Ratte (2)
Reaktivitäten Human (106), Ratte (Rattus) (60), Maus (56), Hund (6), Affe (6), Rind (Kuh) (5), Kaninchen (3), Huhn (2), Meerschweinchen (2), Fruchtfliege (Drosophila melanogaster) (1), Orang-Utan (1), Schaf (1)
Applikationen Western Blot (WB) (95), Immunhistochemie (Paraffinschnitte) (IHC (p)) (47), Immunpräzipitation (IP) (37), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (24), Immunhistochemie (IHC) (19), Enzyme Immunoassay (EIA) (14), Immunfluoreszenz (IF) (14), ELISA (12), Durchflusszytometrie (FACS) (10), Immunzytochemie (ICC) (5), ELISA (Detektionsantikörper) (3), Dot Blot (Dot) (2), Funktionale Studien (Func) (1)
Epitope C-Term (4), N-Term (2), AA 2-295 (1), Ab-286 (1), Center (1), S90 (1), pThr286 (1)