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Prostate Stem Cell Antigen (PSCA) Antikörper

Antigen

Prostate Stem Cell Antigen (PSCA)
Synonyme PRO232, MGC123434, 2210408B04Rik, PSCA
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Alternativen

Human
Applikation
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN125633
Menge 500µl  (100ug/ml approximately)  (Varianten)
Preis 303,85 €   Zzgl. Versandkosten €20,00 und MWSt
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Produktbeschreibung
Anwendungen Alternativen Varianten zurück nach oben

Immunogen A synthetic peptide derived from extracellular region of human PSCA protein.
Format Ig-fraction, Purified
Spezifität This antibody reacts with a ~14 kD protein. Prostate Stem Cell Antigen (PSCA) is a cell surface antigen which is overexpressed in ~ 40% of primary prostate cancers and in nearly 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model.

Anwendungen
Alternativen Varianten zurück nach oben

Applikationshinweise Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Bladder carcinoma, prostate carcinoma. Cellular localization: Cell membrane, cytoplasmic
Konzentration 100ug/ml approximately
Buffer Purified immunoglobulin fraction of rabbit antiserum against PSCA containing sodium azide as preservative.
Lagerung Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Forschungsgebiet Zell-/Gewebemarker, Krebs
Beschränkungen Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Alternativen
Anwendungen Varianten zurück nach oben

Alternativen zu Antigen "Prostate Stem Cell Antigen (PSCA)", Typ "Antikörper" finden
Wirte Kaninchen (45), Ziege (4), Maus (4)
Reaktivitäten Human (50), Maus (4), Hund (2), Rind (Kuh) (1)
Applikationen Durchflusszytometrie (FACS) (18), Immunfluoreszenz (IF) (18), Immunhistochemie (Paraffinschnitte) (IHC (p)) (17), Western Blot (WB) (15), Enzyme Immunoassay (EIA) (10), ELISA (5), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (2), Immunpräzipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunhistochemie (IHC) (1)
Konjugate Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope Center (2)