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TIMP Metallopeptidase Inhibitor 2 (TIMP2) Antikörper

Antigen

TIMP Metallopeptidase Inhibitor 2 (TIMP2)

Synonyme CSC-21K, MGC84288, MGC108274, TIMP-2, TIMP2, timp2
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN125611
Menge 500µl  (100ug/ml approximately)  (Varianten)
Preis 283,65 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung

Weitere Bezeichnung Tissue Inhibitor of Metalloproteinase-2 (TIMP-2)
Immunogen A synthetic peptide from the N-terminal half of human TIMP-2 protein.
Format Ig-fraction, Purified
Spezifität This antibody reacts with a 21kD protein. The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of matrix metalloproteinases (MMPs) and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent and active forms of Type IV collagenase (MMP-2). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Anwendungen

Applikationshinweise Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Colon carcinoma. Cellular localization: Cytoplasmic
Konzentration 100ug/ml approximately
Buffer Purified immunoglobulin fraction of rabbit antiserum against TIMP-2 containing sodium azide as preservative.
Lagerung Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Forschungsgebiet Krebs, Extrazelluläre Matrix, Inflammation
Beschränkungen Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Alternativen

Alternativen zu Antigen "TIMP Metallopeptidase Inhibitor 2 (TIMP2)", Typ "Antikörper" finden
Wirte Maus (62), Kaninchen (57), Schaf (4), Ziege (3)
Reaktivitäten Human (114), Maus (47), Ratte (Rattus) (38), Kaninchen (29), Schwein (24), Rind (Kuh) (23), Huhn (7), Meerschweinchen (6), Zebrafisch (Danio rerio) (6), Hund (2), Affe (2), Schaf (1)
Applikationen Western Blot (WB) (90), Immunhistochemie (Paraffinschnitte) (IHC (p)) (53), Immunfluoreszenz (IF) (38), Durchflusszytometrie (FACS) (23), ELISA (20), Immunpräzipitation (IP) (20), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (16), Enzyme Immunoassay (EIA) (15), Immunhistochemie (IHC) (5), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (7), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope N-Term (3)