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Antikörper
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anti-TIMP Metallopeptidase Inhibitor 2 (TIMP2) Antikörper
TIMP Metallopeptidase Inhibitor 2 (TIMP2) Antikörper
| Antigen |
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| Synonyme |
CSC-21K, MGC84288, MGC108274, TIMP-2, TIMP2, timp2 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Human (114), Maus (47), Ratte (Rattus) (38), Kaninchen (29), Schwein (24), Rind (Kuh) (23), Huhn (7), Meerschweinchen (6), Zebrafisch (Danio rerio) (6), Hund (2), Affe (2), Schaf (1)
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Applikation
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Western Blot (WB) (90), Immunhistochemie (Paraffinschnitte) (IHC (p)) (53), Immunfluoreszenz (IF) (38), Durchflusszytometrie (FACS) (23), ELISA (20), Immunpräzipitation (IP) (20), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (16), Enzyme Immunoassay (EIA) (15), Immunhistochemie (IHC) (5), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN125611 |
| Menge |
500µl (100ug/ml approximately) (Varianten) |
| Preis |
283,65 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 Werktagen |
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Weitere Bezeichnung
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Tissue Inhibitor of Metalloproteinase-2 (TIMP-2)
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Immunogen
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A synthetic peptide from the N-terminal half of human TIMP-2 protein.
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Format
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Ig-fraction, Purified
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Spezifität
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This antibody reacts with a 21kD protein. The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of matrix metalloproteinases (MMPs) and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent and active forms of Type IV collagenase (MMP-2). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
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Applikationshinweise
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Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Colon carcinoma. Cellular localization: Cytoplasmic
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Konzentration
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100ug/ml approximately
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Buffer
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Purified immunoglobulin fraction of rabbit antiserum against TIMP-2 containing sodium azide as preservative.
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Lagerung
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Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
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Forschungsgebiet
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Krebs, Extrazelluläre Matrix, Inflammation
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Beschränkungen
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Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.
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Alternativen zu Antigen "TIMP Metallopeptidase Inhibitor 2 (TIMP2)", Typ "Antikörper" finden
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Wirte
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Maus (62), Kaninchen (57), Schaf (4), Ziege (3)
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Reaktivitäten
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Human (114), Maus (47), Ratte (Rattus) (38), Kaninchen (29), Schwein (24), Rind (Kuh) (23), Huhn (7), Meerschweinchen (6), Zebrafisch (Danio rerio) (6), Hund (2), Affe (2), Schaf (1)
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Applikationen
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Western Blot (WB) (90), Immunhistochemie (Paraffinschnitte) (IHC (p)) (53), Immunfluoreszenz (IF) (38), Durchflusszytometrie (FACS) (23), ELISA (20), Immunpräzipitation (IP) (20), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (16), Enzyme Immunoassay (EIA) (15), Immunhistochemie (IHC) (5), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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Biotin (7), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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N-Term (3)
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