Matrix Metalloproteinase 10 (MMP10) Antikörper

Antigen: Matrix Metalloproteinase 10 (MMP10)

Synonyme: MMP-X1, MTMMP1, MT1-MMP, MMP18, RASI-1, SL-2, MMP-10, AV377895, MGC123370, MMP19

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN125610

Produktbeschreibung

Immunogen: A synthetic peptide from the hinge domain of human MMP-10.

Format: Ig-fraction, Purified

Spezifität: This antibody reacts with a 57 kD protein (pro form) and 44 kD (active form) of MMP-10. Matrix metalloproteinase (MMPs) are a family of closely related zinc-containing proteolytic enzymes, capable of degrading connective tissue components. MMP-10 demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein and nonhelical region of collagen.

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Suitable for formalin fixed paraffin tissue sections. No special pretreatment is required. Positive Control: Placenta. Cellular localization: Cytoplasmic

Konzentration: 100ug/ml approximately

Buffer: Purified immunoglobulin fraction of rabbit antiserum against MMP-10 containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Forschungsgebiet: Extrazelluläre Matrix

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.