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Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antikörper

Antigen

Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)
Synonyme CAP4, MACH, MCH5, FLICE, ALPS2B, Casp-8, FLJ17672, MGC78473, Mch5, Caspase-8, MGC92075, caspase-8, zgc:92075, casp8-A, xCaspase-8, CASP8, casp8, DKFZp469A1428
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Alternativen

Human
Applikation
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN125607
Menge 500µl  (100ug/ml approximately)  (Varianten)
Preis 257,69 €   Zzgl. Versandkosten €20,00 und MWSt
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Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung
Anwendungen Alternativen Sekundärantikörper Varianten zurück nach oben

Weitere Bezeichnung FLICE
Immunogen A synthetic peptide derived from the C-terminus of human I-FLICE.
Format Ig-fraction, Purified
Spezifität This antibody reacts with a 28-58 kD protein. I-FLICE, also known as Casper, is known to inhibit TNFR-1 and CD95 induced apoptosis. It is catalytically inactive form of Caspase 8 and Caspase 10 and binds to them. It contains two death effector domains and a Caspase like domain. Four splice variants of C-FLIP/I-FLICE have been identified and designated FLIP alpha, beta, gamma, delta respectively. They vary in their molecular weights from 28 to 58 kD.

Anwendungen
Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Placenta. Cellular localization: Cytoplasmic Other Applications: Immunofluorescence
Konzentration 100ug/ml approximately
Buffer Purified immunoglobulin fraction of rabbit antiserum against I-FLICE containing sodium azide as preservative.
Lagerung Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Beschränkungen Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Alternativen
Anwendungen Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8)", Typ "Antikörper" finden
Wirte Kaninchen (85), Maus (36), Ratte (4), Huhn (1)
Reaktivitäten Human (115), Maus (54), Ratte (Rattus) (51), Rind (Kuh) (28), Hund (17), Huhn (16), Schwein (16), Affe (12), Schimpanse (2), Kaninchen (2), Pferd (1), Nerz (1)
Applikationen Western Blot (WB) (91), Immunhistochemie (Paraffinschnitte) (IHC (p)) (26), Durchflusszytometrie (FACS) (24), Immunpräzipitation (IP) (23), Immunfluoreszenz (IF) (22), ELISA (13), Enzyme Immunoassay (EIA) (10), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (10), Immunhistochemie (IHC) (8), Dot Blot (Dot) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), ELISA (Fangantikörper) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (3), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope N-Term (8), C-Term (7), active (5), Cleaved-Asp384 (2), Ab-347 (1), Middle (1), active/cleaved (1), pSer347 (1), pTyr380 (1)