Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) Antikörper

Antigen: Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6)

Synonyme: MCH2, Mch2, mCASP-6, MGC93335, xCaspase-6, mch2, caspase-6, CASP6, MGC127633, zgc:112960, casp6

Klonalität: Monoklonal (6CSP03)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN125472

Produktbeschreibung

Weitere Bezeichnung: Caspase 6

Immunogen: BALB/C mice were immunized with recombinant human Caspase 6 prodomain.

Format: Purified

Isotyp: IgG1 kappa  (Passende Sekundärantikörper)

Klon: 6CSP03

Spezifität: This antibody stains with a 34 kD protein, known as Caspase 6. Caspases play a major role in the transduction of the apoptotic signal and execution of apoptosis in mammalian cells. Caspase 3 (CPP32) and Caspase 6 (Mch2) are the major active caspases in apoptotic cells and are activated in response to distinct apoptosis-inducing stimuli. Caspase 6 cleaves nuclear mitotic apparatus protein and medicates the shrinkage and fragmentation of nuclei.

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Tonsil. Cellular localization: Cytoplasmic

Konzentration: 100ug/ml approximately

Buffer: This antibody is supplied as purified ascites containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Forschungsgebiet: Apoptose/Nekrose

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.