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Ataxia Telangiectasia Mutated (ATM) Antikörper
| Antigen | Ataxia Telangiectasia Mutated (ATM) |
| Synonyme | AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, DKFZp781A0353, AI256621, C030026E19Rik, ATM, Tefu, atm/tefu, dATM, tef, DmelCG6535, CG6535, Xatm |
| Klonalität | Monoklonal (ATX08) |
| Wirt |
 Alternativen Maus |
| Reaktivität |
Alternativen Human, Maus |
| Applikation |
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p))
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| Produktnummer | ABIN125439 |
| Menge | 500ul (100ug/ml approximately) (Varianten) |
| Preis | 319,23 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 5 Werktagen |
Produktbeschreibung
| Immunogen | BALB/C mice were injected with recombinant human ATM protein. |
| Format | Ig-fraction |
| Isotyp | IgG1 (Passende Sekundärantikörper) |
| Klon | ATX08 |
| Spezifität | This antibody reacts with a 350 kD protein known as ATM (Ataxia Telangiectasia Mutated). ATM protein phosphorylates p53 on serine 15 near the N terminus, thereby contributing to the activation and stabilization of p53 during the IR-induced DNA damage response. This antibody cross reacts with mouse. |
Anwendungen
| Applikationshinweise | Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the end user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Breast carcinoma. Cellular localization: Nuclear |
| Konzentration | 100ug/ml approximately |
| Buffer | This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative. |
| Lagerung | Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label. |
| Beschränkungen | Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen. |
Alternativen
Alternativen zu Antigen "Ataxia Telangiectasia Mutated (ATM)", Typ "Antikörper" finden
| Wirte | Kaninchen (78), Maus (38), Ziege (13), Huhn (3), Schaf (2) |
| Reaktivitäten | Human (129), Maus (65), Ratte (Rattus) (28), Affe (13), Hamster (4) |
| Applikationen | Western Blot (WB) (85), Immunfluoreszenz (IF) (48), Immunpräzipitation (IP) (47), Immunhistochemie (Paraffinschnitte) (IHC (p)) (20), Durchflusszytometrie (FACS) (18), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (16), Immunhistochemie (IHC) (12), ELISA (11), Enzyme Immunoassay (EIA) (10), Immunzytochemie (ICC) (3), Dot Blot (Dot) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1) |
| Konjugate | Agarose Beads (2), Biotin (2), HRP (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitope | pSer1981 (20), Ab-1981 (5), ppS1981 (1) |
