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Antikörper
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anti-MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) Antikörper
MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2) Antikörper
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| Synonyme |
FCC1, COCA1, HNPCC, LCFS2, HNPCC1, AI788990 |
| Klonalität |
Monoklonal (25D12) |
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Wirt
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Reaktivität
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Applikation
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Western Blot (WB) (41), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Immunfluoreszenz (IF) (24), Durchflusszytometrie (FACS) (21), Immunpräzipitation (IP) (14), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (10), Immunhistochemie (IHC) (10), ELISA (9), Enzyme Immunoassay (EIA) (7), Immunzytochemie (ICC) (3), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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| Produktnummer |
ABIN125437 |
| Menge |
500ul (100ug/ml approximately) (Varianten) |
| Preis |
264,42 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 Werktagen |
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Weitere Bezeichnung
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Mismatch Repair Protein (MSH2)
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Immunogen
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BALB/C mice were injected with recombinant human MSH2 protein.
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Format
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Supernatant
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Isotyp
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IgG1 kappa (Passende Sekundärantikörper)
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Klon
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25D12
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Spezifität
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This antibody reacts with a 102 kD protein known as MSH2 (Mismatch Repair protein 2). MSH2 protein is involved in the initial recognition of mismatched nucleotides during the post replication mismatch repair process. Loss of MSH2 function leads to the accumulation of replication errors, which in turn may be responsible for the multiple mutations required for multistage carcinogenesis.
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Applikationshinweise
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Titer/Working Dilution: This antibody may be diluted to a titer of 1:10-1:25 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the end user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Tonsil. Cellular localization: Nuclear
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Konzentration
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100ug/ml approximately
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Buffer
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This antibody is supplied as tissue culture supernatant containing sodium azide as preservative.
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Lagerung
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Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
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Beschränkungen
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Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.
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Alternativen zu Antigen "MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) (MSH2)", Typ "Antikörper" finden
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Wirte
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Kaninchen (52), Maus (27)
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Reaktivitäten
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Human (75), Maus (25), Ratte (Rattus) (22), Rind (Kuh) (2), Schwein (2), Huhn (1), Hund (1), Fruchtfliege (Drosophila melanogaster) (1), Primate (1)
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Applikationen
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Western Blot (WB) (41), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Immunfluoreszenz (IF) (24), Durchflusszytometrie (FACS) (21), Immunpräzipitation (IP) (14), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (10), Immunhistochemie (IHC) (10), ELISA (9), Enzyme Immunoassay (EIA) (7), Immunzytochemie (ICC) (3), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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Agarose Beads (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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C-Term (1)
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Alternativen 
