Xeroderma Pigmentosum, Complementation Group A (XPA) Antikörper

Antigen: Xeroderma Pigmentosum, Complementation Group A (XPA)

Synonyme: XP1, XPAC, Xpac, AI573865

Klonalität: Monoklonal (12F5)

Wirt: Maus

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN125436

Produktbeschreibung

Weitere Bezeichnung: Xeroderma Pigmentosum Group A Protein (XPA)

Immunogen: BALB/C mice were injected with recombinant human XPA protein.

Format: Ig-fraction

Isotyp: IgG2a kappa

Klon: 12F5

Spezifität: This antibody reacts with a 40 kD protein known as XPA (Xeroderma pigmentosum group A) protein. XPA specifically recognizes the UV or chemically damaged DNA lesions and triggers the nucleotide excision repair process. XPA binds to the replication protein A (RPA) or excision repair cross complementing 1 protein (ERCC1).

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the end user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Tonsil. Cellular localization: Nuclear Other Applications: Western Blotting

Konzentration: 100ug/ml approximately

Buffer: This antibody is supplied as purified immunoglobulin fraction containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.