Transforming Growth Factor, beta S (TGF-beta s) Antikörper

Antigen: Transforming Growth Factor, beta S (TGF-beta s)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN125321

Produktbeschreibung

Weitere Bezeichnung: Transforming Growth Factor-beta s (TGF-beta s)

Immunogen: A synthetic peptide derived from the C-terminal of the precursor form of human TGFbetas protein.

Format: Ig-fraction

Spezifität: Transforming growth factor betas (TGF beta) mediate many cell-cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGFbeta1, TGFbeta2 and TGFbeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. This antibody reacts with the precursor and mature form of TGFbeta2 and to a lesser extent TGFbeta3, but does not cross react with TGFbeta1 or TGFbeta2.This antibody cross reacts with mouse and rat.

Anwendungen

Applikationshinweise: Titer/Working Dilution: This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Placenta. Cellular localization: Cytoplasmic

Konzentration: 100ug/ml approximately

Buffer: Purified immunoglobulin fraction of rabbit antiserum against TGFbeta s protein containing sodium azide as preservative.

Lagerung: Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.

Forschungsgebiet: Zytokine, Wachstumsfaktoren, Rezeptoren, Immunologie, Inflammation

Beschränkungen: Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Bilder

Formalin fixed paraffin embedded human placenta stained with TGFbeta3 antibody