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Epidermal Growth Factor Receptor (EGFR) Antikörper

Antigen

Epidermal Growth Factor Receptor (EGFR)

Synonyme
ERBB, HER1, mENA, ERBB1, PIG61, Wa5, wa2, Erbb, Errp, wa-2, AI552599, 9030024J15Rik, ErbB-1, C-erb, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DmHD-33,  ... mehr anzeigen
Klonalität Monoklonal (SP9)
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN125304
Menge 6ml  (1 to 4 ug/ml)  (Varianten)
Preis 162.00 $   Zzgl. Versandkosten $35.00
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Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung

Immunogen A synthetic peptide from C-terminus of human EGFR protein.
Format Supernatant (prediluted)
Isotyp IgG  (Passende Sekundärantikörper)
Klon SP9
Spezifität This antibody recognizes EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, 02, 03, -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-alpha (TGF-alpha), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head, neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.This antibody crossreacts with Human.
Synonyme ERBB, HER1, mENA, ERBB1, PIG61, Wa5, wa2, Erbb, Errp, wa-2, AI552599, 9030024J15Rik, ErbB-1, C-erb, D-EGFR, D-Egf, DEGFR, DER, DER flb, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DmHD-33, EFG-R, EGF-R, EGFR, EK2-6, Egf, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, HD-33, Torpedo/DER, Torpedo/Egfr, c-erbB, d-egf-r, dEGFR1, flb, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57EFa, l(2)57Ea, pnt, top, top/DER, top/flb, DmelCG10079, CG10079, egfr, EGFR12, EGFR15, egfr1, Erbb2

Anwendungen

Applikationshinweise Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. No pretreatment is required for formalin fixed paraffin tissue sections. Positive Control: Placenta, Lung. Cellular localization: Cytoplasmic, cell membrane
Konzentration 1 to 4 ug/ml
Buffer This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required.
Lagerung Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Beschränkungen Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Alternativen

Alternativen zu Antigen "Epidermal Growth Factor Receptor (EGFR)", Typ "Antikörper" finden
Wirte Kaninchen (391), Maus (166), Ratte (8), Schaf (7), Ziege (2)
Reaktivitäten Human (555), Maus (263), Ratte (Rattus) (238), Hund (33), Kaninchen (18), Schwein (17), Rind (Kuh) (6), Huhn (5), Pferd (2), Schaf (2)
Applikationen Western Blot (WB) (401), Immunhistochemie (Paraffinschnitte) (IHC (p)) (131), Immunpräzipitation (IP) (120), Enzyme Immunoassay (EIA) (103), Immunhistochemie (IHC) (103), Immunfluoreszenz (IF) (95), ELISA (92), Durchflusszytometrie (FACS) (90), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (40), Blocking Antibody (Inhibition) (16), Dot Blot (Dot) (14), Immunzytochemie (ICC) (10), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), Funktionale Studien (Func) (3), ELISA (Detektionsantikörper) (2), Immunoelectron Microscopy (IEM) (2), Neutralisierung (Neut) (2), Blockierende Antikörper (Inhibition) (1)
Konjugate Biotin (35), FITC (5), Alexa Fluor 488 (3), PE (3), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), HRP (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitope pTyr1197 (17), C-Term (16), pTyr869 (13), pTyr1092 (12), pTyr1110 (11), pTyr1172 (11), pThr678 (10), pSer1070 (9), pThr693 (9), N-Term (5), pTyr1016 (3), pTyr1069 (3), AA 1-203 (2), AA 1140-1160 (2), AA 960-980 (2), Extracell. non Ligand binding Site (2), S695 (2), Y1125 (2), Y869 (2), Y998 (2), pSer1071 (2), pTyr1173 (2), AA 1189-1199 (1), AA 985-996 (1), Ab-1016 (1), Ab-1026 (1), Ab-1069 (1), Ab-1071 (1), Amino Acids 1165-1186 (1), External Domain (1), Extracellular non-ligand binding site (1), S1026 (1), S1070 (1), S1071 (1), S1166 (1), S1190 (1), S991 (1), T678 (1), TYR1173 (1), Y1016 (1), Y1069 (1), Y1092 (1), Y1110 (1), Y1172 (1), Y978 (1), extracellular ligand binding site (1), internal (1), pS1070 (1), pS768 (1), pSer1026 (1), pSer1166 (1), pSer1190 (1), pSer695 (1), pSer768 (1), pTyr1125 (1), pTyr992 (1), pTyr998 (1), pY1016 (1), pY1092 (1), pY1172 (1), prylated At Threonine 654 (1), prylated At Tyrosine 1045 (1), prylated At Tyrosine 1173 (1), prylated At Tyrosine 845 (1), prylated at Serine 1047 (1)