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Tumor Protein P53 (TP53) Antikörper

Antigen

Tumor Protein P53 (TP53)

Synonyme p53, LFS1, TRP53, FLJ92943, P53, Trp53, MGC112612, brp53, drp53, fb40d06, wu:fb40d06, zgc:111919, TP53, bbl, bfy, bhy, p44, Tp53, tp53
Klonalität Monoklonal (SP5)
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN125300
Menge 6ml  (1 to 4 ug/ml)  (Varianten)
Preis 168.00 $   Zzgl. Versandkosten $35.00
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Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung

Weitere Bezeichnung p53
Immunogen Recombinant human full-length wild type p53 protein.
Format Supernatant (prediluted)
Isotyp IgG  (Passende Sekundärantikörper)
Klon SP5
Spezifität This antibody recognizes p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.This antibody crossreacts with Human.

Anwendungen

Applikationshinweise Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Colon carcinoma. Cellular localization: Nuclear
Konzentration 1 to 4 ug/ml
Buffer This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required.
Lagerung Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Forschungsgebiet Transkriptionsfaktoren
Beschränkungen Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Alternativen

Alternativen zu Antigen "Tumor Protein P53 (TP53)", Typ "Antikörper" finden
Wirte Kaninchen (254), Maus (80), Schaf (3)
Reaktivitäten Human (328), Maus (68), Ratte (Rattus) (62), Affe (5), Katze (3), Rind (Kuh) (3), Pferd (3), Hund (2), Hamster (2), Primate (2), Primaten (2), Schaf (2), Kaninchen (1), Xenopus laevis (1)
Applikationen Western Blot (WB) (279), Immunhistochemie (Paraffinschnitte) (IHC (p)) (85), Immunhistochemie (IHC) (81), ELISA (68), Immunfluoreszenz (IF) (61), Immunpräzipitation (IP) (41), Enzyme Immunoassay (EIA) (40), Durchflusszytometrie (FACS) (27), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (26), Immunzytochemie (ICC) (11), Dot Blot (Dot) (8), Transfizierte Zellkultur (TCC) (3), Radioimmunoassay (RIA) (2), Chromatin-Immunopräzipitation (ChiP) (1)
Konjugate FITC (7), Biotin (2), HRP (1), PE (1)
Epitope pSer37 (11), pSer315 (10), pSer33 (9), pSer46 (9), pThr18 (9), pSer392 (8), pSer6 (8), pSer15 (7), AA 371-380 (5), pSer20 (5), pSer32/Ser36 (5), AA 20-25 (4), pSer1232 (4), AA 18-30 (3), C-Term (3), S315 (2), S37 (2), S46 (2), T55 (2), pSer9 (2), AA 16-30 (1), AA 378-393 (1), AA 46-53 (1), AA 46-55 (1), Acetyl-Lys317 (1), Acetyl-Lys379 (1), S15 (1), S376 (1), S378 (1), S9 (1), T18 (1), amino acids 211-220 (1), pS20 (1), pS33 (1), pSer376 (1), pSer378 (1), pThr55 (1), phospho (1)