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Tumor Protein P53 (TP53) Antikörper

Antigen

Tumor Protein P53 (TP53)

Synonyme p53, LFS1, TRP53, FLJ92943, P53, Trp53, MGC112612, brp53, drp53, fb40d06, wu:fb40d06, zgc:111919, TP53, bbl, bfy, bhy, p44, Tp53, tp53
Klonalität Monoklonal (SP5)
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p))
Produktnummer ABIN125279
Menge 500ul  (100ug/ml approximately)  (Varianten)
Preis 245.00 $   Zzgl. Versandkosten $35.00
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Verfügbarkeit Lieferung in 5 Werktagen

Produktbeschreibung

Weitere Bezeichnung p53
Immunogen Recombinant human full-length wild type p53 protein.
Format Supernatant
Isotyp IgG  (Passende Sekundärantikörper)
Klon SP5
Spezifität This antibody recognizes p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.This antibody crossreacts with Human.

Anwendungen

Applikationshinweise Titer/Working Dilution: This antibody may be diluted to a titer of 1:100 in an ABC method. However, depending on the staining conditions employed, we suggest that final dilution should be determined by the user. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Positive Control: Colon carcinoma. Cellular localization: Nuclear
Konzentration 100ug/ml approximately
Buffer This antibody is supplied as tissue culture supernatant containing sodium azide as preservative.
Lagerung Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Forschungsgebiet Transkriptionsfaktoren
Beschränkungen Für Forschungszwecke. Als CE-zertifizierter Antikörper in der Europäischen Union für In Vitro Diagnostik (IVD) zugelassen.

Alternativen

Alternativen zu Antigen "Tumor Protein P53 (TP53)", Typ "Antikörper" finden
Wirte Kaninchen (254), Maus (80), Schaf (3)
Reaktivitäten Human (328), Maus (68), Ratte (Rattus) (62), Affe (5), Katze (3), Rind (Kuh) (3), Pferd (3), Hund (2), Hamster (2), Primate (2), Primaten (2), Schaf (2), Kaninchen (1), Xenopus laevis (1)
Applikationen Western Blot (WB) (279), Immunhistochemie (Paraffinschnitte) (IHC (p)) (85), Immunhistochemie (IHC) (81), ELISA (68), Immunfluoreszenz (IF) (61), Immunpräzipitation (IP) (41), Enzyme Immunoassay (EIA) (40), Durchflusszytometrie (FACS) (27), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (26), Immunzytochemie (ICC) (11), Dot Blot (Dot) (8), Transfizierte Zellkultur (TCC) (3), Radioimmunoassay (RIA) (2), Chromatin-Immunopräzipitation (ChiP) (1)
Konjugate FITC (7), Biotin (2), HRP (1), PE (1)
Epitope pSer37 (11), pSer315 (10), pSer33 (9), pSer46 (9), pThr18 (9), pSer392 (8), pSer6 (8), pSer15 (7), AA 371-380 (5), pSer20 (5), pSer32/Ser36 (5), AA 20-25 (4), pSer1232 (4), AA 18-30 (3), C-Term (3), S315 (2), S37 (2), S46 (2), T55 (2), pSer9 (2), AA 16-30 (1), AA 378-393 (1), AA 46-53 (1), AA 46-55 (1), Acetyl-Lys317 (1), Acetyl-Lys379 (1), S15 (1), S376 (1), S378 (1), S9 (1), T18 (1), amino acids 211-220 (1), pS20 (1), pS33 (1), pSer376 (1), pSer378 (1), pThr55 (1), phospho (1)