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Antikörper
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anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) Antikörper
SUMO1 Activating Enzyme Subunit 2 (UBA2) Antikörper
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| Synonyme |
ARX, SAE2, FLJ13058, HRIHFB2115 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN123519 |
| Menge |
0.1 mg (0.5 mg/ml) (Varianten) |
| Preis |
300,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: SUMO-activating enzyme subunit 2, UBLE1B, ARX, HRIHFB2115, Ubiquitin-like 1-activatingenzyme E1B, Anthracycline-associated resistance ARX
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Weitere Bezeichnung
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SAE2 / UBA2
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Gen-ID
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10054
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Swiss-Prot
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Q9UBT2
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Immunogen
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Synthetic peptide within amino acid residues 160-210 of human SAE2
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Beschreibung
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Covalent attachment of one protein to another is one of the more prominentposttranslational modifications in respect to size and ubiquity. Ubiquitin is the mostfamiliar of the protein modifiers and its activation and transfer to target proteins has beenstudied extensively. Recently, a new group of ubiquitin-like proteins has been receiving alot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicatedin the stabilization of target proteins and/or their localization to sub-cellular complexes. The conjugation of SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires theconcerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugatingenzyme Ubc9, and an E3-like SUMO ligase.
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Spezifität
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This antibody is specific for SAE2. Species: Human, Mouse, Rat. Others not tested.
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Applikationshinweise
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Western blot: 0.5 - 2.0 ug/ml. Recommended positive control: HeLa cell lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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0.5 mg/ml
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Buffer
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PBS containing 0.2% gelatin and 0.05% sodium azide
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Lagerung
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Store the antibody at 2-8°C for one month or at -20°C for longer. Avoid repeated freezingand thawing. Shelf life: one year from despatch.
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Forschungsgebiet
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Proteolyse / Ubiquitin
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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