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Activating Transcription Factor 2 (ATF2) Antikörper

Antigen

Activating Transcription Factor 2 (ATF2)

Synonyme HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2, MGC142504, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human

Applikation
Alternativen Western Blot (WB)
2 Publikationen vorhanden
Produktnummer ABIN123294
Menge 0.1 mg  (0.5 mg/ml)  (Varianten)
Preis 280,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Versandbereit innerhalb von 7 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung ATF2
Swiss-Prot P15336
Immunogen Swiss-Prot ID: P15336
Beschreibung ATF-2 is a member of the group of bZip transcription factors. Heterodimer formation between members of the bZip group is common and is believed to add diversity to the cis-acting elements at which binding of the dimers is directed. Specifically, ATF-2 may dimerize with c-Jun, as occurs in response to E1a, and in so doing shift the binding preference of c-Jun toward ATF/CRE sites (1-3). Deletion analysis has indicated that the N-terminal region of ATF-2 containing threonine at residues 69 and 71 are essential for this purpose. These threonine residues are phosphorylated by JNK/SAPK for transcriptional activation.
Spezifität This antibody was generated by immunizing rabbits with a synthetic peptide containing amino acids 13-27.

Anwendungen

Applikationshinweise Western blot: 2 ug/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 0.5 mg/ml
Buffer PBS containing 0.02% sodium azide.
Lagerung Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Forschungsgebiet Immunologie, Angeborene Immunität, Transkriptionsfaktoren
Beschränkungen Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen Hai, Curran: "Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 9, pp. 3720-4, 1991 (PubMed).

Benbrook, Jones: "Heterodimer formation between CREB and JUN proteins." in: Oncogene, Vol. 5, Issue 3, pp. 295-302, 1990 (PubMed).

Alternativen

Alternativen zu Antigen "Activating Transcription Factor 2 (ATF2)", Typ "Antikörper" finden
Wirte Kaninchen (164), Maus (17), Ziege (5), Schaf (5)
Reaktivitäten Human (186), Maus (128), Ratte (Rattus) (113), Huhn (2), Xenopus laevis (2), Rind (Kuh) (1), Hund (1), Pferd (1)
Applikationen Western Blot (WB) (118), Immunhistochemie (IHC) (63), Immunhistochemie (Paraffinschnitte) (IHC (p)) (50), Immunfluoreszenz (IF) (39), Immunpräzipitation (IP) (39), Enzyme Immunoassay (EIA) (31), ELISA (24), Durchflusszytometrie (FACS) (14), Dot Blot (Dot) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (7), ELISA (Detektionsantikörper) (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunelektronenmikroskopie (EM) (1)
Konjugate Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pThr69/51 (7), pSer62/44 (6), pThr71/53 (6), Ab-112 or 94 (5), Ab-62 or 44 (5), Ab-69 or 51 (5), Ab-71 or 53 (5), Ab-73 or 55 (5), pSer112 or 94 (5), pSer62 or 44 (5), pThr69 or 51 (5), pThr71 or 53 (5), pThr73 or 55 (5), pSer112/94 (4), pThr73/55 (4), S44 (2), S94 (2), pThr71 (2), PSer340/322 (1), S322 (1), pSer44 (1), pSer472 (1), pSer490 + pSer498 (1), pSer94 (1), pThr51 (1), pThr69/51 + pThr71/53 (1), pThr79/51 (1)