Cholinergic Receptor, Muscarinic 1 (CHRM1) Antikörper

Antigen: Cholinergic Receptor, Muscarinic 1 (CHRM1)

Synonyme: M1, HM1, M1R, MGC30125, Chrm-1, mAChR, CHRM1, DKFZp459P0517

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN122728

Produktbeschreibung

Weitere Bezeichnung: Muscarinic acetylcholine receptor M1

Swiss-Prot: P11229

Immunogen: Fusion protein containing amino acids 269-320 from human m1 AChR.

Beschreibung: Acetylcholine receptors (AChRs) mediate synaptic transmission at the neuromuscular junction. The channel-linked AChR that mediates rapid, excitatory actions of acetylcholine is called nicotinic AChR (nAChR) because it can be activated by nicotine. The non-channel linked AChR that medicates the slow actions of acetylcholine, which can be either inhibitory or excitatory, is called muscarinic AChR (mAChR) because it can be activated by muscarine. The mAChRs are present in neurons of the central and peripheral nervous systems, cardiac and smooth muscle and various exocrine glands. There are 5 subtypes (m1-m5) of the receptor that have a tissue specific pattern of expression. The m1 receptor is localized primarily in brain tissue. Alternate Names: Muscarinic acetylcholine receptor M1, CHRM1.

Spezifität: ABIN122728 detects recombinant muscarinic acetylcholine receptor 1 (m1AChR). This sequence is completely conserved in mouse, rat, and bovine protein

Anwendungen

Applikationshinweise: Western Blot (2 ug/ml): detects an ~64 kDa protein representing recombinant mouse m1AChR. This antibody is not recommended for Immunohistochemistry procedures. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 1.0 mg/ml

Buffer: PBS containing 1 mg/ml BSA as stabilizer and 0.05% Sodium Azide as preservative.

Lagerung: Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Forschungsgebiet: Neurotransmitter , Hormone, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Figure 1 shows a Western blot on recombinant m1AChR using ABIN122728.