CDC7 Antikörper (Kinase Domain)

Produktnummer ABIN122614

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CDC7 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CDC7 Antikörper (Kinase Domain) (ABIN122614)

Target: CDC7 (Cell Division Cycle 7 (CDC7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC7 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CDC7 Antikörper

Bindungsspezifität: Kinase Domain

Spezifität: Reacts with CDC7-Related Protein Kinase (CDC7L1) (family: Protein Kinase, subfamily: CDC7)

Produktmerkmale: Synonyms: CDC7L1, CDC7-related kinase, HsCdc7, huCdc7, Cell division cycle 7-related protein kinase

Aufreinigung: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugatedEpitope: Kinase domain of humanGenename: CDC7Remarks: The immunizing peptide shows 63 % identity (79 % similarity) with mouse.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin embedded sections: 5,2 μg/mLntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CDC7

Target: CDC7 (Cell Division Cycle 7 (CDC7))

Andere Bezeichnung: CDC7

Hintergrund: CDC7L1, CDC7 type protein kinase, regulates firing of the origins of initiation in DNA replication. CDC7L1 forms a complex with a Dbf4-related regulatory subunit to generate an active kinase. Mini-chromosome maintenance protein (MCM) is the major physiological target of Cdc7L1. At least three mRNA variants have been reported. Overexpression of the CDC7L1 protein may be associated with neoplastic transformation for some tumors. CDC7L1 has been documented in a wide range of tissues. One variant is expressed ubiquitously in human tissues while at least one other has been shown to be testis-specific. ESTs have been isolated from several tissue libraries, including normal embryo, gallbladder, lymph node and thymus and cancerous duodenum and embryo.Synonyms: CDC7-related kinase, CDC7L1, Cell division cycle 7-related protein kinase, HsCdc7, huCdc7

Gen-ID: 8317

UniProt: O00311

Pathways: Mitotic G1-G1/S Phases, DNA Replication