Chemokine (C-C Motif) Receptor 9 (CCR9) Antikörper

Antigen: Chemokine (C-C Motif) Receptor 9 (CCR9)

Synonyme: GPR28, CDw199, GPR-9-6, D6, hD6, CCR9, CCR10, CMKBR9, MGC126678, MGC138250

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p))

Produktnummer: ABIN121958

Produktbeschreibung

Weitere Bezeichnung: CDw199 / CCR9

Swiss-Prot: P51686

Immunogen: Synthetic petide - KLH conjugated.

Beschreibung: CCR9, a chemokine receptor, is expressed in thymocytes and T lymphocytes from the small intestine and colon but not in lymphocytes from tonsils, lung, inflamed liver, normal or inflamed skin, inflamed synovium and synovial fluid, breast milk, and seminal fluid (Kunkel et al., 2000). CCR9 is not detected in natural killer cells, monocytes, eosinophils, basophils, and neutrophils. CCR9 binds TECK (thymus-expressed chemokine), a CC chemokine expressed in thymus and small intestine. TECK chemoattracts dendritic cells, thymocytes, and activated macrophages. Alternate Names: CDW199, CMKBR9, g protein-coupled receptor gpr-9-6, gpr-9-6 Caution: CCR9 and C-C chemokine receptor 9 are valid synonyms for both this receptor, also known as GPR-9-6, and the unrelated chemokine receptor D6..

Spezifität: Reacts with human Chemokine Receptor 9 (.The immunizing peptide shows 76% identity (88% similarity) with mouse and rat

Anwendungen

Applikationshinweise: Immunohistochemistry on paraffin embedded sections. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Konzentration: 1 mg/ml

Buffer: PBS, pH 7.7, containing 0.01% sodium azide

Lagerung: Store the antibody at 2-8°C for one month or at -70°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Forschungsgebiet: Chemokine, Rezeptoren

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Staining of human thymus with ABIN121958