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MADCAM1 Antikörper

MADCAM1 Reaktivität: Human WB, FACS, IHC (p), EIA Wirt: Maus Monoclonal 17F5 unconjugated
Produktnummer ABIN120242
  • Target Alle MADCAM1 Antikörper anzeigen
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    Reaktivität
    • 45
    • 45
    • 7
    • 1
    Human
    Wirt
    • 47
    • 15
    • 6
    Maus
    Klonalität
    • 47
    • 21
    Monoklonal
    Konjugat
    • 25
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MADCAM1 Antikörper ist unkonjugiert
    Applikation
    • 57
    • 34
    • 26
    • 26
    • 16
    • 13
    • 10
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM-1). Clone 17F5 recognises the Mucin domain of MAdCAM-1. This antibody does not block the function of MAdCAM-1.
    Aufreinigung
    Affinity Chromatography on Protein G.
    Immunogen
    Recombinant soluble MAdCAM-1-fc fusion protein. Spleen cells from immunised Balb/c mice were fused with cells of the mouse P3X63Ag8.653 myeloma cell line.
    Klon
    17F5
    Isotyp
    IgG1
  • Applikationshinweise
    Flow Cytometry: 1/10- 1/100, use 10 μL of the suggested working dilution to label 106 cells in 100 μL. Immunohistochemistry on paraffin embedded sections: 1/50 - 1/100, This product does not require protein digestion prior to staining, This product does not require HIER prior to staining. ELISA. Western Blot: under reducing conditions, This antibody detects a band of approximately 60 kDa.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
    Andere Bezeichnung
    MAdCAM1 (MADCAM1 Produkte)
    Synonyme
    MACAM1 antikoerper, AV211525 antikoerper, mucosal vascular addressin cell adhesion molecule 1 antikoerper, MADCAM1 antikoerper, Madcam1 antikoerper
    Hintergrund
    Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM-1) is a 60kD transmembrane protein that belongs to the immunoglobulin superfamily. MAdCAM-1 is strongly expressed on mucosal lymphoid tissue and high endothelial venules of Peyers patches. Human MAdCAM-1 interacts with the beta 7 integrin LPAM-1 (alpha4beta7), CD62L, and VLA-4 (alpha4beta1) and is involved in lymphocyte trafficking.Synonyms: MAdCAM-1, Mucosal addressin cell adhesion molecule 1, hMAdCAM-1
    Gen-ID
    8174
    NCBI Accession
    NP_570116
    UniProt
    Q13477
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