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LAMP2 Antikörper (Lysosomal-Associated Membrane Protein 2) (FITC)

Details für Produkt anti-LAMP2 Antikörper Nr. ABIN120162, Anbieter: Anmelden zum Anzeigen
Antigen
  • cd107b
  • lamp-2
  • lampb
  • LAMP2
  • lamp2
  • DKFZp459J126
  • LAMP-2
  • LGP-B
  • CD107b
  • Lamp-2
  • Lamp-2a
  • Lamp-2b
  • Lamp-2c
  • Mac3
  • LAMPB
  • LGP110
  • lysosomal-associated membrane protein 2
  • Lysosome-associated membrane glycoprotein 2
  • lysosomal membrane glycoprotein B
  • LAMP2
  • lamp2
  • LOC100218047
  • LOC100222683
  • Lgpb
  • Lamp2
Reaktivität
Maus
285
185
39
26
19
6
2
2
Wirt
Ratte
162
147
117
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser LAMP2 Antikörper ist konjugiert mit FITC
52
39
29
23
11
10
7
6
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS)
225
189
99
99
98
93
82
61
56
11
8
5
4
2
2
2
2
2
2
1
1
1
1
1
Optionen
Hersteller
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Bilder

Immunogen Glycoproteins purified from Mouse peritoneal Macrophage membranes. Spleen cells from immunised Lewis rats were fused with cells of the mouse P3-NSI/1-Ag4-1 myeloma cell line.
Klon M3-84
Isotyp IgG1
Spezifität This antibody recognises CD107b, also known as MAC-3 and LAMP-2. The expression of CD107b is predominantly cytoplasmic.
Kreuzreaktivität (Details) Species reactivity (tested):Mouse.
Reinigung Affinity Chromatography on Protein G.
Andere Bezeichnung CD107b / LAMP2 (LAMP2 Antibody Abstract)
Hintergrund CD107b is a transmembrane glycoprotein that is associated with lysosomal membranes and is primarily expressed on mononuclear phagocytes. Expression of CD107b does vary between cell populations and the molecular weight of CD107b can vary between 92-120kD. Studies suggest that CD107b may be involved in leucocyte adhesion.Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2
Gen-ID 16784
NCBI Accession NP_001017959
UniProt P17047
Forschungsgebiet CD Antigens, Surface Receptors of Immune Cells
Applikationshinweise Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, Results may be enhanced using permeabilisation, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing. This product is photosensitive and should protected from light.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-LAMP2 Antikörper (Lysosomal-Associated Membrane Protein 2)  (FITC) (ABIN120162) Staining of permeabilised mouse peritoneal macrophages with RAT ANTI MOUSE CD107b: FI...
Allgemeine Veröffentlichungen Flotte, Springer, Thorbecke: "Dendritic cell and macrophage staining by monoclonal antibodies in tissue sections and epidermal sheets." in: The American journal of pathology, Vol. 111, Issue 1, pp. 112-24, 1983 (PubMed).

Ho, Springer: "Tissue distribution, structural characterization, and biosynthesis of Mac-3, a macrophage surface glycoprotein exhibiting molecular weight heterogeneity." in: The Journal of biological chemistry, Vol. 258, Issue 1, pp. 636-42, 1983 (PubMed).

Springer: "Monoclonal antibody analysis of complex biological systems. Combination of cell hybridization and immunoadsorbents in a novel cascade procedure and its application to the macrophage cell surface." in: The Journal of biological chemistry, Vol. 256, Issue 8, pp. 3833-9, 1981 (PubMed).