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HLAG Antikörper

HLAG Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal MEM-G-1 unconjugated
Produktnummer ABIN119227
  • Target Alle HLAG Antikörper anzeigen
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    Reaktivität
    • 125
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 66
    • 65
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 69
    • 67
    Monoklonal
    Konjugat
    • 52
    • 20
    • 19
    • 15
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HLAG Antikörper ist unkonjugiert
    Applikation
    • 86
    • 69
    • 59
    • 43
    • 30
    • 27
    • 15
    • 13
    • 13
    • 11
    • 10
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody reacts with denatured soluble and membrane bound HLA G heavy chain.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity Chromatography on Protein A
    Immunogen
    Denatured bacterially expressed recombinant Human HLA G heavy chain
    Klon
    MEM-G-1
    Isotyp
    IgG1
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  • Applikationshinweise
    Western Blot. Immunohistochemistry on paraffin sections: This product requires antigen retrieval using heat treatment prior to staining of paraffin sections, Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommended Positive Control: Human placenta.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
    Andere Bezeichnung
    HLA Class I alpha G / HLA-G (HLAG Produkte)
    Synonyme
    MHC-G antikoerper, B-F antikoerper, B-F-S04 antikoerper, B-F-S05 antikoerper, B-F-S06 antikoerper, B-F-S07 antikoerper, B-FI antikoerper, B-FIV antikoerper, BF2 antikoerper, BFa2 antikoerper, BFw-03 antikoerper, BFw-05 antikoerper, BFz-01 antikoerper, major histocompatibility complex, class I, G antikoerper, MHC BF1 class I antikoerper, HLA-G antikoerper, BF1 antikoerper
    Hintergrund
    The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. HLA G belongs to the HLA class I molecules (HLA Class Ib, nonclassical) and is involved in the presentation of foreign antigens to the immune system. This molecule is expressed on the surface of trophoblast cells and plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T lymphocytes, macrophages and mononuclear cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.0, HLAG, MHC class I antigen G
    Molekulargewicht
    38 kDa.
    Gen-ID
    3135
    NCBI Accession
    NP_002118
    UniProt
    P17693
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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