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TSH receptor Antikörper

TSHR Reaktivität: Human WB, FACS, IHC (p), IP, EIA Wirt: Maus Monoclonal 2C11 unconjugated
Produktnummer ABIN119039
  • Target Alle TSH receptor (TSHR) Antikörper anzeigen
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Reaktivität
    • 78
    • 54
    • 35
    • 9
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 67
    • 14
    • 1
    • 1
    Maus
    Klonalität
    • 68
    • 15
    Monoklonal
    Konjugat
    • 44
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TSH receptor Antikörper ist unkonjugiert
    Applikation
    • 44
    • 41
    • 20
    • 14
    • 14
    • 13
    • 13
    • 9
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    Spezifität
    2C11 recognises both native and denatured TSH receptor (binding to an epitope at the carboxy terminus between amino acids 354 and 359). It does inhibit binding of TSH. No cross reactivity has been observed with related LH and FSH receptors. This antibody recognises the mutant TSH receptor known as I167N as well as the wild type molecule.
    Aufreinigung
    Affinity chromatography on Protein G
    Immunogen
    Recombinant Human TSH receptor. Spleen cells from immunised BALB/c mice were fused with cells of the NS1/Ag4.1 mouse myeloma cell line.
    Klon
    2C11
    Isotyp
    IgG1
    Top Product
    Discover our top product TSHR Primärantikörper
  • Applikationshinweise
    Flow Cytometry. ELISA. Immunoprecipitation: 5-10 μg/mL. Western Blot: 5-10 μg/mL. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Andere Bezeichnung
    Thyrotropin Receptor / TSHR (TSHR Produkte)
    Synonyme
    CHNG1 antikoerper, LGR3 antikoerper, hTSHR-I antikoerper, AI481368 antikoerper, hypothroid antikoerper, hyt antikoerper, pet antikoerper, TSHRA antikoerper, TSH-R antikoerper, thyroid stimulating hormone receptor antikoerper, tshr antikoerper, TSHR antikoerper, Tshr antikoerper
    Hintergrund
    The thyroid stimulating hormone (TSH) receptor (otherwise known as the thyrotropin receptor) is an important molecule in controlling the growth and function of the normal thyroid.Synonyms: LGR3, TSH-R, TSH-receptor, Thyroid-stimulating hormone receptor
    Gen-ID
    7253
    NCBI Accession
    NP_000360
    UniProt
    P16473
    Pathways
    Thyroid Hormone Synthesis
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