Tumor Necrosis Factor Antikörper (TNF) (AA 115-130)

Details for Product anti-TNF Antibody No. ABIN118949, Anbieter: Anmelden zum Anzeigen
Antigen
  • TNF
  • tnf
  • dif
  • tnfa
  • xtnf
  • TNF-a
  • tnfsf2
  • tnf-alpha
  • TNF-alpha
  • DIF
  • TNFA
  • TNFSF2
  • TNFalpha
  • Tnfa
  • Tnfsf1a
  • RATTNF
  • TNFa
  • cTNF
  • TNF-ALPHA
  • Cachectin
  • Tnf-alpha
  • tnfa-like
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor
  • tumour necrosis factor alpha-like
  • tumor necrosis factor alpha
  • lipopolysaccharide-induced TNF factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • TNF
  • tnf
  • tnf-alpha
  • LITAF
  • Tnf
  • tnfb
Epitop
AA 115-130
52
44
33
27
24
22
18
17
15
11
11
10
10
8
8
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
1258
465
359
145
136
119
119
63
55
41
29
18
14
12
9
7
6
4
4
4
4
2
1
1
1
1
Wirt
Maus
941
521
186
49
10
9
7
6
4
3
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
169
100
78
50
32
30
28
27
26
25
25
25
25
25
24
24
24
23
13
9
8
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
888
860
632
322
287
230
221
191
139
117
97
68
30
29
26
22
20
18
14
9
8
7
6
6
6
6
5
5
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen 115-130 sequence linked to thyroglobulin. Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0-Ag14 myeloma cell line.
Klon 4C6-H6
Isotyp IgM
Reinigung Supernatant
Andere Bezeichnung Tumor Necrosis Factor (TNF-Alpha) (TNF Antibody Abstract)
Hintergrund Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
Gen-ID 9606
UniProt P01375
Forschungsgebiet Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Cancer, Virology
Pathways NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus
Applikationshinweise Flow Cytometry: Membrane permeabilisation is required for this application. ELISA: 1/2 - 1/10. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer 0.2 M Tris/HCl pH 7.4 containing 5-10 % Foetal Calf Serum, 0.09 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Allgemeine Veröffentlichungen Bebök, Márkus, Németh: "Prognostic relevance of transforming growth factor alpha (TGF-alpha) and tumor necrosis factor alpha (TNF-alpha) detected in breast cancer tissues by immunohistochemistry." in: Breast cancer research and treatment, Vol. 29, Issue 3, pp. 229-35, 1994 (PubMed).

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