FCGR2A Antikörper

Produktnummer ABIN118595

Produktdetails anti-FCGR2A Antikörper

Target: FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FCGR2A Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody recognises the CD32 antigen. Clone AT10 blocks the binding of IgG to Fc gamma R11. SM1092LE is recommended for this purpose.

Aufreinigung: Affinity Chromatography on Protein A.

Immunogen: K562 cell line. Remarks: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

Klon: AT10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation: 20 μg/mL. Flow Cytometry (20 μg/mL): Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Immunohistochemistry on Frozen Sections: 1/500-1/1000. Recommended Positive Control: Lymph node.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FCGR2A

Target: FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))

Andere Bezeichnung: CD32 / FcRII-A (FCGR2A Produkte)

Synonyme: CD32 antikoerper, CD32A antikoerper, CDw32 antikoerper, FCG2 antikoerper, FCGR2 antikoerper, FCGR2A1 antikoerper, FcGR antikoerper, IGFR2 antikoerper, CD32a antikoerper, Fc fragment of IgG receptor IIa antikoerper, FCGR2A antikoerper

Hintergrund: CD32 is a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets.Synonyms: CDw32, FCG2, FCGR2A, FCGR2A1, Fc-gamma RII-a, Fc-gamma-RIIa, IGFR2, IgG Fc receptor II, Low affinity immunoglobulin gamma Fc region receptor II

Gen-ID: 2212

NCBI Accession: NP_001129691

UniProt: P12318