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CD3 Antikörper (PE)

CD3 Reaktivität: Human, Primate FACS Wirt: Maus Monoclonal UCHT1 PE
Produktnummer ABIN118481
  • Target Alle CD3 Antikörper anzeigen
    CD3
    Reaktivität
    • 222
    • 97
    • 31
    • 15
    • 15
    • 10
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    Human, Primate
    Wirt
    • 257
    • 52
    • 14
    • 13
    • 10
    Maus
    Klonalität
    • 334
    • 8
    Monoklonal
    Konjugat
    • 98
    • 36
    • 31
    • 26
    • 24
    • 13
    • 9
    • 9
    • 9
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD3 Antikörper ist konjugiert mit PE
    Applikation
    • 294
    • 93
    • 59
    • 52
    • 45
    • 45
    • 39
    • 24
    • 16
    • 10
    • 9
    • 9
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognises CD3, a 19 kDa cell surface protein which is expressed on more than 95 % of circulating peripheral blood T-cells.
    Aufreinigung
    Affinity chromatography on Protein G
    Immunogen
    Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome.
    Klon
    UCHT1
    Isotyp
    IgG1
    Top Product
    Discover our top product CD3 Primärantikörper
  • Applikationshinweise
    Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore with distilled water.
    Konzentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    This product is photosensitive and should be protected from light
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Target
    CD3
    Andere Bezeichnung
    CD3 (CD3 Produkte)
    Synonyme
    CD3 antikoerper, AI504783 antikoerper, CD3epsilon antikoerper, T3e antikoerper, cd3-gamma antikoerper, cd3g antikoerper, cd3g-a antikoerper, cd3g/d antikoerper, cd3gd antikoerper, t3g antikoerper, CD3e molecule antikoerper, CD3d molecule antikoerper, CD3 antigen, epsilon polypeptide antikoerper, CD3g molecule S homeolog antikoerper, CD3E antikoerper, CD3D antikoerper, Cd3e antikoerper, cd3g.S antikoerper
    Hintergrund
    T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits: CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82 % of normal peripheral blood lymphocytes, 65-85 % of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
    Gen-ID
    916
    NCBI Accession
    NP_000724
    UniProt
    P07766
    Pathways
    T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
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