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TNFRSF4 Antikörper (FITC)

TNFRSF4 Reaktivität: Maus FACS Wirt: Ratte Monoclonal OX-86 FITC
Produktnummer ABIN118271
  • Target Alle TNFRSF4 Antikörper anzeigen
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    Reaktivität
    • 69
    • 53
    • 34
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 56
    • 38
    • 17
    • 2
    Ratte
    Klonalität
    • 58
    • 53
    Monoklonal
    Konjugat
    • 55
    • 12
    • 11
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNFRSF4 Antikörper ist konjugiert mit FITC
    Applikation
    • 61
    • 54
    • 32
    • 16
    • 14
    • 13
    • 12
    • 11
    • 10
    • 8
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognises OX40 (CD134), a cell surface antigen expressed only by activated T lymphocytes.
    Aufreinigung
    Affinity chromatography on Protein G
    Immunogen
    CHO cells transfected with murine OX40. Spleen cells from immunised AO rats were fused with cells of the mouse NS1 myeloma cell line.
    Klon
    OX-86
    Isotyp
    IgG1
    Top Product
    Discover our top product TNFRSF4 Primärantikörper
  • Applikationshinweise
    Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    Andere Bezeichnung
    CD134 / TNFRSF4 (TNFRSF4 Produkte)
    Synonyme
    TNFRSF4 antikoerper, ACT35 antikoerper, CD134 antikoerper, Ly-70 antikoerper, Ox40 antikoerper, TXGP1L antikoerper, Txgp1 antikoerper, OX40 antikoerper, TNF receptor superfamily member 4 antikoerper, tumor necrosis factor receptor superfamily, member 4 antikoerper, TNFRSF4 antikoerper, Tnfrsf4 antikoerper
    Hintergrund
    The OX40 receptor is also known as CD134, ACT35, and tumour necrosis factor receptor superfamily member 4. This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX40 receptor binds to the OX40 ligand to provide a co-stimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, imply that these interactions are important in the pathogenesis of some autoimmune diseases.Synonyms: ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, TNFRSF4, TXGP1L, Tumor necrosis factor receptor superfamily member 4
    Gen-ID
    22163
    NCBI Accession
    NP_035789
    UniProt
    P47741
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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