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ITGA6 Antikörper (FITC)

ITGA6 Reaktivität: Human, Maus, Hund, Schwein, Affe, Schaf FACS Wirt: Ratte Monoclonal NKI-GoH3 FITC
Produktnummer ABIN118232
  • Target Alle ITGA6 Antikörper anzeigen
    ITGA6 (Integrin, alpha 6 (ITGA6))
    Reaktivität
    • 127
    • 61
    • 25
    • 21
    • 15
    • 12
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Hund, Schwein, Affe, Schaf
    Wirt
    • 71
    • 38
    • 25
    • 2
    Ratte
    Klonalität
    • 68
    • 66
    Monoklonal
    Konjugat
    • 71
    • 12
    • 11
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ITGA6 Antikörper ist konjugiert mit FITC
    Applikation
    • 80
    • 54
    • 51
    • 44
    • 23
    • 20
    • 15
    • 13
    • 13
    • 13
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    This antibody recognises CD49F (VLA-6 alpha chain). Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone GoH3 specifically blocks the binding of cells to the E8 fragment of laminin.
    Aufreinigung
    Affinity chromatography on Protein G
    Immunogen
    BALB/c mouse mammary tumour cells. Spleen cells from immunised Sprague-Dawley rats were fused with cells of the SP2/0 mouse myeloma cell line.
    Klon
    NKI-GoH3
    Isotyp
    IgG2a
    Top Product
    Discover our top product ITGA6 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.1 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ITGA6 (Integrin, alpha 6 (ITGA6))
    Andere Bezeichnung
    CD49f / ITGA6 (ITGA6 Produkte)
    Synonyme
    CD49f antikoerper, ITGA6B antikoerper, VLA-6 antikoerper, 5033401O05Rik antikoerper, AI115430 antikoerper, Cd49f antikoerper, ITGA6 antikoerper, inta6 antikoerper, im:6897425 antikoerper, itga6 antikoerper, si:dkey-32o22.1 antikoerper, wu:fb80g02 antikoerper, LOC100221694 antikoerper, si:dkey-18j14.1 antikoerper, wu:fl20e08 antikoerper, zgc:113088 antikoerper, integrin subunit alpha 6 antikoerper, integrin alpha 6 antikoerper, integrin subunit alpha 6 L homeolog antikoerper, integrin, alpha 6a antikoerper, integrin, alpha 6b antikoerper, ITGA6 antikoerper, Itga6 antikoerper, itga6.L antikoerper, itga6a antikoerper, itga6b antikoerper
    Hintergrund
    CD49f is a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells.Synonyms: CD49 antigen-like family member F, Integrin alpha-6, VLA-6, VLA6
    Gen-ID
    3655
    NCBI Accession
    NP_000201
    UniProt
    P23229
    Pathways
    CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex
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