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Aurora Kinase B Antikörper (AA 227-238)

AURKB Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN117978
  • Target Alle Aurora Kinase B (AURKB) Antikörper anzeigen
    Aurora Kinase B (AURKB)
    Bindungsspezifität
    • 21
    • 20
    • 18
    • 13
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 227-238
    Reaktivität
    • 136
    • 70
    • 37
    • 12
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 130
    • 25
    • 3
    • 1
    Kaninchen
    Klonalität
    • 116
    • 44
    Polyklonal
    Konjugat
    • 84
    • 13
    • 10
    • 9
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Aurora Kinase B Antikörper ist unkonjugiert
    Applikation
    • 104
    • 73
    • 50
    • 36
    • 20
    • 14
    • 14
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequenz
    Human Aurora B Kinase, 344 aa, predicted MW 39.3kDa 1 maqkensypw pygrqtapsg lstlpqrvlr kepvtpsalv lmsrsnvqpt aapgqkvmen 61 ssgtpdiltr hftiddfeig rplgkgkfgn vylarekksh fivalkvlfk sqiekegveh 121 qlrreieiqa hlhhpnilrl ynyfydrrri ylileyaprg elykelqksc tfdeqrtati 181 meeladalmy chgkkvihrd ikpenlllgl kgelkiadfg wsvhapslrr ktmcgtldyl 241 ppemiegrmh nekvdlwcig vlcyellvgn ppfesashne tyrrivkvdl kfpasvptga 301 qdliskllrh npserlplaq vsahpwvran srrvlppsal qsva
    Spezifität
    This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase. Reactivity occurs against human Aurora Kinase B protein. No reaction is expected against Aurora Kinase A. However, 100 % sequence homology as indicated by BLAST analysis is on record for this protein from human, mouse, rat, cow, pig, dog and chimpanzee. Cross reactivity with Aurora Kinase B from other sources is not known.
    Aufreinigung
    Immunoaffinity chromatography.
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding aa 227-238 of Human Aurora Kinase B protein.
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  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA (1: 5,000-1: 20,000) and byWestern blot (1: 500-1: 2,000). Specific conditions for reactivity should be optimized by theend user. Expect a band approximately 39 kDa in size corresponding to Aurora Kinase B bywestern blotting in the appropriate cell lysate or extract. Human brain tissue lysate or HeLacell lysate can be used as a positive control.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.45 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Dilute only prior to immediate use
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. This product is stable for one month at 2-8 °C as an undiluted liquid. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
  • Honda, Asato, Tanaka, Endo, Nishimura, Ito: "Vidian nerve schwannoma with middle cranial fossa extension resected via a maxillary swing approach." in: Head & neck, (2008) (PubMed).

  • Target
    Aurora Kinase B (AURKB)
    Andere Bezeichnung
    Aurora Kinase B (AURKB Produkte)
    Synonyme
    AIK2 antikoerper, AIM-1 antikoerper, AIM1 antikoerper, ARK2 antikoerper, AurB antikoerper, IPL1 antikoerper, PPP1R48 antikoerper, STK12 antikoerper, STK5 antikoerper, aurkb-sv1 antikoerper, aurkb-sv2 antikoerper, AIRK2 antikoerper, AL022959 antikoerper, Aik2 antikoerper, Aim1 antikoerper, Ark2 antikoerper, STK-1 antikoerper, Stk12 antikoerper, Stk5 antikoerper, Aur B antikoerper, Aurora B antikoerper, Aurora-B antikoerper, CG6620 antikoerper, DmAIRK2 antikoerper, DmAurB antikoerper, DmAuroraB antikoerper, Dmel\\CG6620 antikoerper, IAL antikoerper, IAL1 antikoerper, Ial antikoerper, aurB antikoerper, aurora B antikoerper, ARK-2 antikoerper, XAIRK2 antikoerper, aik2 antikoerper, aim-1 antikoerper, aim1 antikoerper, airk2 antikoerper, ark2 antikoerper, ipl1 antikoerper, stk12 antikoerper, stk5 antikoerper, CHUNP6896 antikoerper, fa09g06 antikoerper, stka antikoerper, wu:fa09g06 antikoerper, aurkb antikoerper, AIRK2-B antikoerper, XAIRK2-B antikoerper, aurkb-a antikoerper, aurkb-b antikoerper, xAurora-B-B antikoerper, aurora kinase B antikoerper, aurora B antikoerper, aurora kinase B S homeolog antikoerper, AURKB antikoerper, Aurkb antikoerper, aurB antikoerper, aurkb antikoerper, aurkb.S antikoerper
    Hintergrund
    Aurora Kinase B (also known as Aurora- and Ipl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, and Aurora-B) is a Ser/Thr protein kinase member of the Aurora subfamily that may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Aurora Kinase B is localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis and is colocalized with gamma tubulin in the mid-body. High levels of Aurora B expression are seen in the thymus, although it is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase.Synonyms: AIK2, AIM1, ARK2, AURKB, Aurora- and Ipl1-like midbody-associated protein 1, Aurora-B, Aurora/IPL1-related kinase 2, STK-1, STK12, Serine/threonine-protein kinase 12
    Gen-ID
    9212
    NCBI Accession
    NP_004208
    UniProt
    Q96GD4
    Pathways
    T-Zell Rezeptor Signalweg, Zellzyklus, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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