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ANAPC2 Antikörper (C-Term)

ANAPC2 Reaktivität: Human WB, EIA, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN117942
  • Target Alle ANAPC2 Antikörper anzeigen
    ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 810-822, C-Term
    Reaktivität
    • 25
    • 12
    • 4
    • 1
    Human
    Wirt
    • 19
    • 6
    Kaninchen
    Klonalität
    • 20
    • 4
    Polyklonal
    Konjugat
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ANAPC2 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 11
    • 9
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
    Sequenz
    Human APC2 (822 aa 93.8 kDa): 1 maaavvvaeg dsdsrpgqel lvawntvstg lvppaalglv ssrtsgavpp keeelraave 61 vlrghglhsv leewfvevlq ndlqanispe fwnaisqcen sadepqclll lldafglles 121 rldpylrsle llekwtrlgl lmgtgaqglr eevhtmlrgv lffstprtfq emiqrlygcf 181 lrvymqskrk geggtdpele geldsryarr ryyrllqspl cagcssdkqq cwcrqaleqf 241 hqlsqvlhrl sllervsaea vtttlhqvtr ermedrcrge yersflrefh kwiervvgwl 301 gkvflqdgpa rpaspeagnt lrrwrchvqr ffyriyaslr ieelfsivrd fpdsrpaied 361 lkyclertdq rqqllvslka aletrllhpg vntcdiitly isaikalrvl dpsmvileva 421 cepirrylrt redtvrqiva gltgdsdgtg dlavelsktd pasletgqds eddsgepedw 481 vpdpvdadpg kssskrrssd iisllvsiyg skdlfineyr slladrllhq fsfspereir 541 nvellklrfg eapmhfcevm lkdmadsrri nanireedek rpaeeqppfg vyavilssef 601 wppfkdekle vpediraale ayckkyeqlk amrtlswkht lglvtmdvel adrtlsvavt 661 pvqavillyf qdqaswtlee lskavkmpva llrrrmsvwl qqgvlreepp gtfsvieeer 721 pqdrdnmvli dsddesdsgm asqadqkeee lllfwtyiqa mltnleslsl driynmlrmf 781 vvtgpalaei dlqelqgylq kkvrdqqlvy sagvyrlpkn cs
    Spezifität
    This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This antibody reacts with human APC2. Cross reactivity may also occur with APC2 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2.
    Aufreinigung
    Delipidation and defibrination.
    Immunogen
    This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 810-822 of Human APC2 (C- terminal) coupled to KLH.
    Top Product
    Discover our top product ANAPC2 Primärantikörper
  • Applikationshinweise
    Western blot (1: 500-1: 1,000). Immunoprecipitation: The antibody immunoprecipitates in vitro translated protein andprotein from overexpressing cell lysates (using HeLa and NIH-3T3, and others. Coimmunoprecipitation of related proteins (APC11) does occur. A 93.8 kDa bandcorresponding to human APC2 is detected. Most cell lines or tissues expressing APC2 canbe used as a positive control. ELISA (1: 2,000-1: 10,000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    85 mg/mL (by Refractometry)
    Handhabung
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Wang, Yu, Xiang, Fan, He, Guo, Feng, Deng: "Global transcriptional profiles of Staphylococcus aureus treated with berberine chloride." in: FEMS microbiology letters, Vol. 279, Issue 2, pp. 217-25, (2008) (PubMed).

  • Target
    ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))
    Andere Bezeichnung
    APC2 / ANAPC2 (ANAPC2 Produkte)
    Synonyme
    anapc2 antikoerper, ANAPC2 antikoerper, DDBDRAFT_0203816 antikoerper, DDBDRAFT_0234264 antikoerper, DDB_0203816 antikoerper, DDB_0234264 antikoerper, si:ch73-203i15.5 antikoerper, APC2 antikoerper, RP11-350O14.5 antikoerper, 9230107K09Rik antikoerper, AL024279 antikoerper, Apc2 antikoerper, Emi4 antikoerper, Imi4 antikoerper, mKIAA1406 antikoerper, F28I8.30 antikoerper, F28I8_30 antikoerper, anaphase-promoting complex/cyclosome 2 antikoerper, anaphase promoting complex subunit 2 antikoerper, anaphase promoting complex subunit 2 L homeolog antikoerper, anaphase-promoting complex/cyclosome 2 antikoerper, Anaphase-promoting complex subunit 2 antikoerper, ANAPC2 antikoerper, anapc2.L antikoerper, anapc2 antikoerper, Anapc2 antikoerper, APC2 antikoerper, apc-2 antikoerper
    Hintergrund
    APC2, also known as Anaphase promoting complex subunit 2, APC2, Cyclosome subunit 2, and ANAPC2, is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/cyclosome protein complex promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitors, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains at least eleven subunits. The composition of APC is highly conserved in organisms from yeast to humans. APC2 is a cullin family member that interacts through the cullin domain with ANAPC11 and UBCH10.Synonyms: Anaphase-promoting complex subunit 2, Cyclosome subunit 2, KIAA1406
    Gen-ID
    29882
    NCBI Accession
    NP_037498
    UniProt
    Q9UJX6
    Pathways
    Regulation of Cell Size
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