DCLRE1C Antikörper (AA 482-495)
-
- Target Alle DCLRE1C Antikörper anzeigen
- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
-
Bindungsspezifität
- AA 482-495
-
Reaktivität
- Human
-
Wirt
- Ziege
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser DCLRE1C Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects a band of the appropriate size in a number of different cell lines. However, it does not detect a band in cell lines that do not express ARTEMIS, such as the cell line CJ and in an hTERT line.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Immunoaffinity Chromatography using the immunizing peptide after immobilization to a solid phase.
- Immunogen
- This antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross- link repair 1C). Genename: DCLRE1C
- Top Product
- Discover our top product DCLRE1C Primärantikörper
-
-
- Applikationshinweise
-
This antibody has been tested for use in ELISA (1: 10,000-1: 20,000), Immunohistochemistry(1: 1,000) and Western blotting (1: 500-1: 2,000). Reactivity in other immunoassays isunknown. This antibody detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.2 mg/mL (by UV absorbance at 280 nm)
- Buffer
- 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, with 0.01 %(w/v) Sodium Azide as preservative.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid.
-
- Target
- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
- Andere Bezeichnung
- Artemis (DCLRE1C Produkte)
- Synonyme
- artemis antikoerper, A-SCID antikoerper, DCLREC1C antikoerper, RS-SCID antikoerper, SCIDA antikoerper, SNM1C antikoerper, hSNM1C antikoerper, Snm1l antikoerper, nuclease antikoerper, 9930121L06Rik antikoerper, AI661365 antikoerper, Art antikoerper, DNA cross-link repair 1C antikoerper, DCLRE1C antikoerper, Dclre1c antikoerper
- Hintergrund
- Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNAPKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C
- Gen-ID
- 64421
- NCBI Accession
- NP_001029027
- UniProt
- Q96SD1
- Pathways
- DNA Reparatur
-