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DCLRE1C Antikörper (AA 482-495)

DCLRE1C Reaktivität: Human WB, IHC (p), EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN117935
  • Target Alle DCLRE1C Antikörper anzeigen
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 482-495
    Reaktivität
    • 44
    • 28
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 59
    • 1
    Ziege
    Klonalität
    • 60
    Polyklonal
    Konjugat
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DCLRE1C Antikörper ist unkonjugiert
    Applikation
    • 46
    • 28
    • 23
    • 13
    • 13
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects a band of the appropriate size in a number of different cell lines. However, it does not detect a band in cell lines that do not express ARTEMIS, such as the cell line CJ and in an hTERT line.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Immunoaffinity Chromatography using the immunizing peptide after immobilization to a solid phase.
    Immunogen
    This antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross- link repair 1C). Genename: DCLRE1C
    Top Product
    Discover our top product DCLRE1C Primärantikörper
  • Applikationshinweise
    This antibody has been tested for use in ELISA (1: 10,000-1: 20,000), Immunohistochemistry(1: 1,000) and Western blotting (1: 500-1: 2,000). Reactivity in other immunoassays isunknown. This antibody detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.2 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, with 0.01 %(w/v) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid.
  • Target
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    Andere Bezeichnung
    Artemis (DCLRE1C Produkte)
    Synonyme
    artemis antikoerper, A-SCID antikoerper, DCLREC1C antikoerper, RS-SCID antikoerper, SCIDA antikoerper, SNM1C antikoerper, hSNM1C antikoerper, Snm1l antikoerper, nuclease antikoerper, 9930121L06Rik antikoerper, AI661365 antikoerper, Art antikoerper, DNA cross-link repair 1C antikoerper, DCLRE1C antikoerper, Dclre1c antikoerper
    Hintergrund
    Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNAPKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C
    Gen-ID
    64421
    NCBI Accession
    NP_001029027
    UniProt
    Q96SD1
    Pathways
    DNA Reparatur
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