Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) Antikörper

Details zu Produkt Nr. ABIN1169331, Anbieter: Anmelden zum Anzeigen
Antigen
  • Gitrl
  • AITRL
  • GITRL
  • TL6
  • hGITRL
  • TNLG2A
  • tumor necrosis factor (ligand) superfamily, member 18
  • TNF superfamily member 18
  • Tnfsf18
  • TNFSF18
Reaktivität
Maus
146
63
18
2
2
1
Wirt
Ratte
77
73
33
2
Klonalität (Klon)
Monoklonal ()
Konjugat
Unkonjugiert
10
8
7
6
5
5
5
5
5
5
4
4
4
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
90
86
78
13
7
6
5
4
4
4
4
4
2
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Recombinant mouse GITRL.
Klon MGTL 15
Isotyp IgG2a
Fragment kappa
Spezifität Recognizes mouse GITRL. Detects a band of ~25 kDa by Western blot.
Kreuzreaktivität Maus
Keine Kreuzreaktivität Human
Kreuzreaktivität (Details) Does not cross-react with human GITRL.
Sterilität 0.2 μm filtered
Andere Bezeichnung GITRL (TNFSF18 Antibody Abstract)
Hintergrund GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, ..). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
UniProt Q7TS55
Forschungsgebiet Growth Factors
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Konservierungsmittel Without preservative
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Haltbarkeit 12 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) antibody (ABIN1169331) Western blot analysis using anti-GITRL (mouse), mAb (MGIT 15) at 1:5'000 dilution. 1...
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