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MEFV Antikörper (AA 2-29)

MEFV Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1169260
  • Target Alle MEFV Antikörper anzeigen
    MEFV (Mediterranean Fever (MEFV))
    Bindungsspezifität
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 2-29
    Reaktivität
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 19
    • 2
    • 1
    Kaninchen
    Klonalität
    • 21
    • 1
    Polyklonal
    Konjugat
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser MEFV Antikörper ist unkonjugiert
    Applikation
    • 17
    • 15
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Spezifität
    Recognizes human pyrin.
    Kreuzreaktivität
    Human
    Immunogen
    Synthetic peptide corresponding to aa 2-29 (A2KTPSDHLLSTLEELVPYDFEKFKFKLQ29) of human pyrin.
    Top Product
    Discover our top product MEFV Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Papin, Cuenin, Agostini, Martinon, Werner, Beer, Grütter, Grütter, Tschopp: "The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing." in: Cell death and differentiation, Vol. 14, Issue 8, pp. 1457-66, (2007) (PubMed).

  • Target
    MEFV (Mediterranean Fever (MEFV))
    Andere Bezeichnung
    Pyrin (MEFV Produkte)
    Synonyme
    pyrin antikoerper, MEFV antikoerper, FMF antikoerper, MEF antikoerper, TRIM20 antikoerper, rfp domain antikoerper, MEFV, pyrin innate immunity regulator antikoerper, Mediterranean fever antikoerper, MEFV antikoerper, Mefv antikoerper
    Hintergrund
    Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.
    UniProt
    O15553
    Pathways
    Positive Regulation of Endopeptidase Activity
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