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CCL19 Antikörper (Biotin)

CCL19 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN116174
  • Target Alle CCL19 Antikörper anzeigen
    CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
    Reaktivität
    • 53
    • 19
    • 5
    • 2
    Human
    Wirt
    • 45
    • 14
    • 1
    Kaninchen
    Klonalität
    • 43
    • 17
    Polyklonal
    Konjugat
    • 29
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCL19 Antikörper ist konjugiert mit Biotin
    Applikation
    • 47
    • 28
    • 25
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    Human Macrophage Inflammatory Protein-3 beta (MIP-3 beta).
    Aufreinigung
    Affinity chromatography.
    Immunogen
    Highly pure (>98%) recombinant hMIP-3 beta (human MIP-3 beta).
    Top Product
    Discover our top product CCL19 Primärantikörper
  • Applikationshinweise
    ELISA: To detect hMIP-3 beta by direct ELISA (using 100 l/well antibody solution) thisantibody can be used at a concentration of 0.15 - 0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthMIP-3 betaWestern Blot: To detect hMIP-3 beta by Western Blot analysis this antibody can be used ata concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hMIP-3 beta is 1.5 - 3.0 ng/lane, under eitherreducing or non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2 without preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
  • Target
    CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
    Andere Bezeichnung
    MIP3-beta / CCL19 (CCL19 Produkte)
    Synonyme
    CKb11 antikoerper, ELC antikoerper, MIP-3b antikoerper, MIP3B antikoerper, SCYA19 antikoerper, CCL19 antikoerper, Scya19 antikoerper, exodus-3 antikoerper, C-C motif chemokine ligand 19 antikoerper, chemokine (C-C motif) ligand 19 antikoerper, CCL19 antikoerper, ccl19 antikoerper, Ccl19 antikoerper
    Hintergrund
    MIP3 chemokines are among many novel beta chemokines recently identified through bioinformatics in the Expressed Sequence Tag (EST) database. They are distantly related to other beta chemokines (20-30 % aa sequence homology). MIP3 chemokines are useful probes for studying the biology of inflammation and cell migration. Their expression is strongly up-regulated by inflammatory signals and down-regulated by the anti-inflammatory cytokine IL10. MIP3 beta is also known as ELC (EBI1-1 ligand chemokine) and is constitutively expressed in various lymphoid tissues (thymus, lymph nodes, appendix and spleen). MIP3 beta is a chemoattractant for cultured human lymphocytes, dendritic cells, human T lymphoblastoid CEM NKR2 and hemopoietic progenitor cells. It may be involved in G Protein activation in human NK cells. MIP3 beta is a unique functional ligand for CCR7. The MIP3 beta gene has been mapped to chormosome 9p13.Synonyms: Beta chemokine exodus-3, C-C motif chemokine 19, CCL-19, CK beta-11, EBI1-ligand chemokine, ELC, Exodus-3, MIP-3 beta, MIP3B, Macrophage inflammatory protein 3 beta, SCYA19, Small-inducible cytokine A19, Small-inducible cytokine A19
    Gen-ID
    6363
    NCBI Accession
    NP_006265
    UniProt
    Q99731
    Pathways
    Positive Regulation of Immune Effector Process
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