FLT3LG Antikörper (Biotin)

Produktnummer ABIN116011

Produktdetails anti-FLT3LG Antikörper (Biotin)

Target: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLT3LG Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: Recognizes Human Flt3-Ligand

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography.

Immunogen: Highly pure (>98%) recombinant Human Flt3-ligand.

Anwendungsinformationen

Applikationshinweise: ELISADirect: To detect Human hFlt3-ligand by direct ELISA (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonalantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant Human Flt3-ligand. Sandwich: To detect Human Flt3-ligand by Sandwich ELISA (using 100 μL/well antibodysolution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylatedpolyclonal antibody, in conjunction with Polyclonal Anti-Human Flt3-ligand (PP1008P1 orPP1008P2) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well ofrecombinant Human Flt3-ligand. Western Blot: To detect hFlt3-ligand by Western Blot analysis this antibody can be used ata concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing. Centrifuge vial prior to opening.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu FLT3LG

Target: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Andere Bezeichnung: Flt3 Ligand (FLT3LG Produkte)

Synonyme: Flt3lg antikoerper, Ly72L antikoerper, FL antikoerper, FLT3L antikoerper, Vegfr3 antikoerper, fms related tyrosine kinase 3 ligand antikoerper, FMS-like tyrosine kinase 3 ligand antikoerper, fms-related tyrosine kinase 4 antikoerper, fms-related tyrosine kinase 3 ligand antikoerper, FLT3LG antikoerper, Flt3l antikoerper, Flt4 antikoerper, Flt3lg antikoerper

Hintergrund: Flt3 ligand is a ligand for the FLT3 tyrosine kinase receptor and belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3 ligand have been identified. The predominant form is the transmembrane form, which is biologically active on the cell surface. When proteolytically cleaved the transmembrane isoform generates a soluble form, which is also biologically active. Flt3 ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3 ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. hflt3-Ligand (flk2-ligand) stimulates the proliferation and colony formation of certain bone marrow precursor cells including CD34+ cells.Synonyms: FLT3LG, Flt3L, SL cytokine, fms-related tyrosine kinase 3 ligand

Gen-ID: 2323

NCBI Accession: NP_001450

UniProt: P49771

Pathways: RTK Signalweg