Angiostatin (ANG) Antikörper

Antigen: Angiostatin (ANG)

Synonyme: DKFZp779M0222, Pg, AI649309, Ab1-346, PLG, LPA, wu:fb70e09, plg, DKFZp470G2422

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Enzyme Immunoassay (EIA), Western Blot (WB)

Produktnummer: ABIN115500

Produktbeschreibung

Produktmerkmale: Synonyms: Plasminogen, PLG

Weitere Bezeichnung: Angiostatin

Swiss-Prot: P00747

Beschreibung: Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis,which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumorgrowth and can maintain metastatic and primary tumors in a dormant state. It is defined bya balance of proliferation and apoptosis of the tumor cells and is composed ofplasminogen first four cringle structures. This molecule is generated by proteolyticcleavage of plasminogen. Recombinant angiostatin has 260 amino acids, residues 97-357of human proplasminogen, and a calculated molecular mass of 29. 8 kDa.

Spezifität: The antibody was raised in rabbits by immunization with the Human Angiostatin fromhuman plasma. Species: Human. Others not tested.

Anwendungen

Applikationshinweise: ELISA. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 1.0 mg/ml

Buffer: 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREEReconstitution: Restore with 0.1 ml of deionized water

Lagerung: Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not showdecline in activity after two weeks at 4°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Forschungsgebiet: Krebs, Angiogenese, Zytokine

Beschränkungen: Nur für Forschungszwecke einsetzbar