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Osteoprotegerin Antikörper (N-Term)
TNFRSF11B
Reaktivität: Human
WB, EIA
Wirt: Maus
Monoclonal
OPG-13
unconjugated
Produktdetails anti-Osteoprotegerin Antikörper
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Target
Alle Osteoprotegerin (TNFRSF11B) Antikörper anzeigen
Osteoprotegerin (TNFRSF11B)
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Bindungsspezifität
Alle Epitope für Osteoprotegerin Antikörper
AA 21-39, N-Term
Reaktivität
Alle Reaktivitäten für Osteoprotegerin Antikörper
Human
Wirt
Alle Wirte für Osteoprotegerin Antikörper
Maus
Klonalität
Alle Klonalitäten für Osteoprotegerin Antikörper
Monoklonal
Konjugat
Alle Konjugate für Osteoprotegerin Antikörper
Dieser Osteoprotegerin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Osteoprotegerin Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
The Anti Human Osteoprotegerin, Clone: OPG-13 is a mouse monoclonal antibody against synthetic peptide of Human Osteoprotegerin.
Aufreinigung
Affinity chromatography on protein G
Immunogen
Synthetic OPG peptide that comprises AA21 to AA39 homologous with human osteoprotegerin (N-terminal C has been added to the peptide)
Klon
OPG-13
Isotyp
IgG1
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Discover our top product TNFRSF11B Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
ELISA. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
Restore with 0.1 mL of deionized water
Konzentration
1.0 mg/mL
Buffer
0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
Konservierungsmittel
Azide free
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
Haltbarkeit
6 months
Details zu Osteoprotegerin
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Target
Osteoprotegerin (TNFRSF11B)
(Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
Andere Bezeichnung
Osteoprotegerin / TNFRSF11B (TNFRSF11B Produkte )
Synonyme
CD254 antikoerper, ODF antikoerper, OPGL antikoerper, OPTB2 antikoerper, RANKL antikoerper, TRANCE antikoerper, hRANKL2 antikoerper, sOdf antikoerper, OCIF antikoerper, OPG antikoerper, TR1 antikoerper, Opg antikoerper, ocif antikoerper, opg antikoerper, tr1 antikoerper, TNF superfamily member 11 antikoerper, TNF receptor superfamily member 11b antikoerper, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antikoerper, TNF receptor superfamily member 11B antikoerper, tumor necrosis factor receptor superfamily member 11b S homeolog antikoerper, tumor necrosis factor receptor superfamily, member 11b antikoerper, TNFSF11 antikoerper, TNFRSF11B antikoerper, Tnfrsf11b antikoerper, tnfrsf11b.S antikoerper
Substanzklasse
Chemical
Hintergrund
Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues, it has a molecular weight of 60 kDa as a monomer and 120 kDa as a disulfide-linked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. Osteoprotegerin inhibits the recruitment, proliferation and activation of osteoclasts. Osteoclast formation activity may be monitored principally by determination of concentration ratio of osteoprotegerin ligand (OPGL)/OPG. Alteration of this ratio may be the cause of bone loss in many imbalances in bone metabolism such as osteoporosis, osteopetrosis, hypercalcemia, metastatic osteolytic lesions and rheumatic bone degradation.Synonyms: OCIF, OPG, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
Gen-ID
4982
NCBI Accession
NP_002537
UniProt
O00300
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