KRT8 Antikörper
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- Target Alle KRT8 Antikörper anzeigen
- KRT8 (Keratin 8 (KRT8))
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Reaktivität
- Human, Ratte, Maus, Kaninchen, Säugetier
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser KRT8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- M20 reacts with glandular epithelial cells (endocrine and exocrine) as well as mesothelial cells of the digestive, respiratory and urogenital tract and most adenocarcinomas derived from these cells. The M20 epitope has been mapped to amino acids 353-367 on the alpha helical rod domain of Cytokeratin 8 (See Reference 10).
- Aufreinigung
- Purified
- Immunogen
- Keratin isolated from the Human breast carcinoma cell line MCF-7
- Klon
- M20
- Isotyp
- IgG1
- Top Product
- Discover our top product KRT8 Primärantikörper
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- Applikationshinweise
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Immunoblotting: 1/100-1/1000Immunocytochemistry. Flow Cytometry. Immunohistochemistry on Frozen Tissues: 1/100-1/200 with Avidin-biotinylatedHorseradish peroxidase complex ABC as detection reagent.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the lyophilized antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. When reconstituted the antibody is stable for one month at 2-8 °C.
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- Target
- KRT8 (Keratin 8 (KRT8))
- Andere Bezeichnung
- Cytokeratin 8 (KRT8 Produkte)
- Synonyme
- CARD2 antikoerper, CK-8 antikoerper, CK8 antikoerper, CYK8 antikoerper, K2C8 antikoerper, K8 antikoerper, KO antikoerper, AA960620 antikoerper, AL022697 antikoerper, AU019895 antikoerper, Card2 antikoerper, EndoA antikoerper, Krt-2.8 antikoerper, Krt2-8 antikoerper, CYKER antikoerper, KRT2-8 antikoerper, KERATIN8 antikoerper, ck8 antikoerper, cyk8 antikoerper, k2c8 antikoerper, card2 antikoerper, krt2-5 antikoerper, MGC69490 antikoerper, KRT8 antikoerper, DreK8 antikoerper, cb186 antikoerper, krt2-8 antikoerper, sb:cb186 antikoerper, wu:fa20h05 antikoerper, wu:fa95h10 antikoerper, wu:fb96c06 antikoerper, zf-K8 antikoerper, zfk8 antikoerper, DKFZp468F2127 antikoerper, keratin 8 antikoerper, keratin 8 S homeolog antikoerper, KRT8 antikoerper, Krt8 antikoerper, krt8.S antikoerper, krt8 antikoerper
- Hintergrund
- Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9-7.8. The individual cytokeratin polypeptides are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8
- Gen-ID
- 3856
- NCBI Accession
- NP_002264
- UniProt
- P05787
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