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CD68 Antikörper (FITC)

CD68 Reaktivität: Human FACS Wirt: Maus Monoclonal Ki-M7 FITC
Produktnummer ABIN112006
  • Target Alle CD68 Antikörper anzeigen
    CD68 (CD68 Molecule (CD68))
    Reaktivität
    • 161
    • 82
    • 44
    • 39
    • 26
    • 14
    • 10
    • 2
    • 2
    • 2
    • 2
    Human
    Wirt
    • 91
    • 89
    • 17
    • 1
    Maus
    Klonalität
    • 113
    • 81
    Monoklonal
    Konjugat
    • 87
    • 16
    • 15
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD68 Antikörper ist konjugiert mit FITC
    Applikation
    • 85
    • 77
    • 51
    • 37
    • 36
    • 34
    • 33
    • 24
    • 14
    • 13
    • 13
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    CD68 antibody BM4111F recognizes the 110KD integral membrane glycoprotein CD68 (Macrosialin) predominantly expressed on the intracellular lysosomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes.
    Produktmerkmale
    Absorption / Emission: 495 nm / 528 nm
    Aufreinigung
    Protein A Chromatography
    Immunogen
    Cell suspensions of Human lymph node
    Klon
    Ki-M7
    Isotyp
    IgG1
    Top Product
    Discover our top product CD68 Primärantikörper
  • Applikationshinweise
    Flow Cytometry: Use 10 μL to label 10^6 cells in 100 μL (Membrane permeabilisation isrequired). Clone KiM7 has been reported as being also suitable for use in Immunoprecipitation andImmunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, 0.05 % Sodium Azide, 1 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    CD68 (CD68 Molecule (CD68))
    Andere Bezeichnung
    CD68 (CD68 Produkte)
    Synonyme
    Lamp4 antikoerper, Scard1 antikoerper, gp110 antikoerper, GP110 antikoerper, LAMP4 antikoerper, SCARD1 antikoerper, CD68 molecule antikoerper, CD68 antigen antikoerper, Cd68 molecule antikoerper, CD68 antikoerper, Cd68 antikoerper
    Hintergrund
    The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukaemia studies.Synonyms: Gp110, Macrophage marker, Macrosialin
    Gen-ID
    968
    NCBI Accession
    NP_001035148
    UniProt
    P34810
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